All CD302 reagents are produced in house and quality controlled, including 4 CD302 Antibody, 39 CD302 Gene, 4 CD302 Lysate, 4 CD302 Protein, 2 CD302 qPCR. All CD302 reagents are ready to use.
Recombinant CD302 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His.
CD302antibodies are validated with different applications, which are ELISA, IHC-P.
CD302cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD302 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function.