All CLEC10A reagents are produced in house and quality controlled, including 3 CLEC10A Antibody, 36 CLEC10A Gene, 3 CLEC10A Lysate, 3 CLEC10A Protein, 3 CLEC10A qPCR. All CLEC10A reagents are ready to use.
Recombinant CLEC10A proteins are expressed by HEK293 Cells with fusion tags as N-human IgG1-Fc, N-His.
CLEC10Aantibodies are validated with different applications, which are ELISA.
CLEC10AcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CLEC10A of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.