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CD300C Antibody, Mouse MAb

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    Human CD300C Antibody Product Information
    Immunogen:Recombinant Human CD300C Protein (Catalog#11832-H08H)
    Clone ID:1A6F8
    Ig Type:Mouse IgG1
    Concentration:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD300C (rh CD300C; Catalog#11832-H08H; NP_006669.1; Met 1-Arg 183). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
    Other CD300C Antibody Products
    CD300C Background

    The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD300 is a glycoprotein family of cell surface molecules that regulate a diverse array of cell processes via their triggering and inhibitory receptor functions. The CD300 family of myeloid immunoglobulin receptors includes activating(CD300b, CD300e) and inhibitory members(CD300a, CD300f), as well as CD300c and CD300d, whose function is uncertain.

    Human CD300C References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Lankry D, et al. (2010) Expression and function of CD300 in NK cells.185(5): 2877-86.
  • Agueda MB, et al. (2010) CD300 heterocomplexes, a new and family-restricted mechanism for myeloid cell signaling regulation. Journal of biological chemistry. 285: 41781-94.
  • Clark GJ, et al. (2009) The CD300 molecules regulate monocyte and dendritic cell functions. 214 (9-10): 730-6.
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    Catalog: 11832-MM01-200
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    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"