CD30 Protein (TNFRSF8 Protein)

Cluster of Differentiation 8 (Tumor Necrosis Factor Receptor Superfamily Member 8)

CD30 Protein Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CD30/TNFRSF8	Human	CD30/Fc Protein, Recombinant	10777-H03H
CD30/TNFRSF8	Human	CD30 Protein, Recombinant	10777-H08H

10777-H03H: Immobilized recombinant human CD30L at 20 µg/ml (100 µl/well) can bind biotinylated human CD30 with a linear range of 0.31-20 ng/ml. Measured by its binding ability in a functional ELISA.

10777-H08H:

1. Measured by its binding ability in a functional ELISA.

2. Immobilized recombinant human CD30 at 2 µg/ml (100 µl/well) can bind human CD30L Fc Chimera with a linear range of 6.4-800 ng/ml.

CD30 Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CD30/TNFRSF8	WB,Elisa	Mouse Monoclonal Antibody	10777-MM01

CD30 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CD30/TNFRSF8	Human	Homo sapiens CD30/TNFRSF8 cDNA Clone	HG10777-M

CD30 Alternative Names

CD30, TNFRSF8, D1S166E, Ki-1 [Homo sapiens]

Cd30, Tnfrsf8, RP23-306F22.1, D1S166E, Ki, Ki-1 [Mus musculus]

CD30 Related Areas

Stem Cell>>Embryonic Stem Cell (ESC)>>Embryonic Stem Cell Marker>>CD30/TNFRSF8

Immunology>>Adaptive Immunity>>Costimulation & Costimulatory Molecule>>CD30/TNFRSF8

Immunology>>Cytokine & Receptor>>TNF Superfamily>>CD30/TNFRSF8

Immunology>>Innate Immunity>>Natural Killer Cell (NK Cell)>>CD30/TNFRSF8

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>> CD30/TNFRSF8

Immunology>>Cluster of Differentiation>>Dendritic Cell CD Antigen>>Dendritic Cell Co-stimulatory Molecules>>CD30/TNFRSF8

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Other>>CD30/TNFRSF8

Immunology>>Cluster of Differentiation>>Natural Killer (NK) Cell CD Antigen>> CD30/TNFRSF8

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Helper T Cells>> CD30/TNFRSF8

CD30 Protein Related Products

Protein Products
Molecule	Species	Description //For Detailed Info. and Price------CLICK!
CD120a/TNFRI /TNFRSF1A	Human	CD120a/Fc Protein, Recombinant
CD120a/TNFRI /TNFRSF1A	Human	CD120a Protein, Recombinant
CD120b/TNFRII/TNFRSF1B	Human	CD120b Protein, Recombinant
CD120b/TNFRII/TNFRSF1B	Human	CD120b/Fc Protein, Recombinant
CD134/TNFRSF4	Human	OX40/CD134/Fc Protein, Recombinant
CD134/TNFRSF4	Human	OX40/CD134 Protein, Recombinant
CD40/TNFRSF5	Human	CD40/TNFRSF5/Fc Protein, Recombinant
CD40/TNFRSF5	Human	CD40 Protein, Recombinant
CD40/TNFRSF5	Mouse	CD40/TNFRSF5 Protein, Recombinant
CD95/APO-1/TNFRSF6	Human	CD95/APO-1/TNFRSF6/Fc Protein, Recombinant
CD95/APO-1/ TNFRSF6	Human	CD95/APO-1/TNFRSF6 Protein, Recombinant
CD95/APO-1/TNFRSF6	Mouse	CD95/APO-1/TNFRSF6 Protein, Recombinant
CD95/APO-1/TNFRSF6	Rat	CD95/APO-1/TNFRSF6 Protein, Recombinant
CD27/TNFRSF7	Human	CD27/TNFRSF7/Fc Protein, Recombinant
CD27/TNFRSF7	Mouse	CD27/TNFRSF7/Fc Protein, Recombinant
CD27/TNFRSF7	Mouse	CD27/TNFRSF7 Protein, Recombinant
CD137/4-1BB/TNFRSF9	Human	4-1BB/TNFRSF9/Fc Protein, Recombinant
CD137/4-1BB/TNFRSF9	Human	CD137/4-1BB/TNFRSF9 Protein, Recombinant
CD137/4-1BB/TNFRSF9	Mouse	CD137/4-1BB/TNFRSF9 Protein, Recombinant
CD261/TRAILR1/TNFRSF10A	Human	TRAIL R1/TNFRSF10A/CD261/Fc Protein, Recombinant
CD261/TRAILR1/TNFRSF10A	Human	TRAIL R1/TNFRSF10A/CD261/Fc Protein, Recombinant
CD261/TRAILR1/TNFRSF10A	Human	TRAIL R1/TNFRSF10A/CD261 Protein, Recombinant
CD262/TRAILR2/TNFRSF10B	Human	TRAILR2/Fc Protein, Recombinant
CD262/TRAILR2/TNFRSF10B	Human	TRAILR2 Protein, Recombinant
CD262/TRAILR2/TNFRSF10B	Mouse	TRAILR2/Fc Protein, Recombinant
CD262/TRAILR2/TNFRSF10B	Mouse	TRAILR2 Protein, Recombinant
CD264/TRAILR4/TNFRSF10D	Human	TRAILR4/Fc Protein, Recombinant
CD264/TRAILR4/TNFRSF10D	Human	TRAILR4 Protein, Recombinant
CD27L/CD70/TNFSF7	Human	CD70/Fc Protein, Recombinant
CD30L/TNFSF8	Human	CD30L/TNFSF8/Fc Protein, Recombinant
CD137L/4-1BBL/TNFSF9	Mouse	4-1BB Ligand Protein, Recombinant
CD137L/4-1BBL/TNFSF9	Human	4-1BB/TNFRSF9/Fc Protein, Recombinant

Antibody Products
Molecule	Application	Description //For Detailed Info. and Price------CLICK!
Human CD120a/TNFRI /TNFRSF1A	WB, ELISA	Rabbit Monoclonal Antibody
Human CD120a/TNFRI /TNFRSF1A	WB, ELISA	Rabbit Polyclonal Antibody
Human CD120a/TNFRI /TNFRSF1A	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human CD134/TNFRSF4	WB, ELISA	OX40/CD134 Antibody, Rabbit PAb
Human CD134/TNFRSF4	WB, ELISA	OX40/CD134 Antibody, Rabbit PAb (Antigen Affinity Purified)
Mouse CD27	WB, ELISA	CD27 Antibody, Rabbit PAb
Mouse CD27	WB, ELISA	CD27 Antibody, Rabbit PAb (Antigen Affinity Purified)
Human CD40/TNFRSF5	WB, ELISA	Mouse Monoclonal Antibody
Human CD40/TNFRSF5	WB, ELISA	CD40/TNFRSF5 Antibody, Rabbit MAb
Human CD40/TNFRSF5	WB, ELISA	Rabbit Polyclonal Antibody
Human CD40/TNFRSF5	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human CD95/APO-1/TNFRSF6	WB, ELISA	CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb
Human CD95/APO-1/TNFRSF6	WB, ELISA	CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb (Antigen Affinity Purified)
Mouse CD95/APO-1/TNFRSF6	WB, ELISA	CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb
Mouse CD95/APO-1/TNFRSF6	WB, ELISA	CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb (Antigen Affinity Purified)
Human CD262/TRAIL R2/TNFRSF10B	WB, ELISA	Rabbit Polyclonal Antibody
Human CD262/TRAIL R2/TNFRSF10B	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Mouse CD262/TRAIL R2/TNFRSF10B	WB, ELISA	TRAIL R2/TNFRSF10B/CD262 Antibody, Rabbit PAb
Mouse CD262/TRAIL R2/TNFRSF10B	WB, ELISA	TRAIL R2/TNFRSF10B/CD262 Antibody, Rabbit PAb (Antigen Affinity Purified)
Mouse CD137L/4-1BBL/TNFSF9	WB, ELISA	Rabbit Monoclonal Antibody
Mouse CD137L/4-1BBL/TNFSF9	ELISA	Rabbit Polyclonal Antibody
Mouse CD137L/4-1BBL/TNFSF9	WB, ELISA	Rabbit Polyclonal Antibody

cDNA Clone Products
Molecule	Species	Description //For Detailed Info. and Price------CLICK!
CD120a/TNFRI /TNFRSF1A	Human	Homo sapiens CD120a/TNFRI cDNA Clone(NM_001065.2)
CD18/TNFRSF3	Human	Homo sapiens TNFRSF3 cDNA Clone(NM_002342.1)
CD134/TNFRSF4	Human	Homo sapiens TNFRSF4 cDNA Clone(NM_003327.2)
CD40/TNFRSF5	Human	Homo sapiens CD40/TNFRSF5 cDNA Clone(NM_001250.4)
CD95/TNFRSF6	Human	Homo sapiens CD95/Fas transcript variant 1 cDNA Clone(NM_000043.3)
CD95/APO-1/ TNFRSF6	Mouse	Mus musculus CD95/APO-1/TNFRSF6 cDNA Clone
CD95/APO-1/ TNFRSF6	Rat	Rattus norvegicus CD95/APO-1/TNFRSF6 cDNA Clone
CD137/4-1BB/TNFSF9	Human	Homo sapiens 4-1BB/TNFRSF9 cDNA Clone(NM_001561.4)
CD261/TRAILR1/TNFRSF10A	Human	Homo sapiens TRAILR1 cDNA Clone(NM_003844.2)
CD262/TRAILR2/TNFRSF10B	Human	Homo sapiens TRAILR2 cDNA Clone(NM_003842.3)
CD262/TRAILR2/TNFRSF10B	Mouse	Mus musculus TRAILR2 cDNA Clone
CD263/TRAILR3/TNFRSF10C	Human	Homo sapiens TRAILR3 cDNA Clone(NM_003841.2)
CD264/TRAILR4/TNFRSF10D	Human	Homo sapiens TRAILR4 cDNA Clone(NM_003840.3)
CD266/TNFRSF12	Human	Homo sapiens TNFRSF12 cDNA Clone(NM_016639.2)
CD27/TNFRSF7	Mouse	Mus musculus CD27/TNFRSF7 cDNA Clone
CD40L/TNFSF5	Human	Homo sapiens CD40L/TNFSF5 cDNA Clone(NM_000074.2)
CD95L/FASL/CD178/TNFSF6	Human	Homo sapiens FasL/TNFSF6 cDNA Clone(NM_000639.1)
CD27L/CD70/TNFSF7	Human	Homo sapiens CD27L/TNFSF7 cDNA Clone(NM_001252.3)
CD30L/CD153/TNFSF8	Human	Homo sapiens CD30L/TNFSF8 cDNA Clone(NM_001244.2)
CD253/ TNFSF10/TRAIL	Human	Homo sapiens TNFSF10/TRAIL cDNA Clone(NM_003810.2)
CD256/TNFSF13	Human	Homo sapiens TNFSF13 cDNA Clone(NM_003808.3)
CD257/TNFSF13B/TNFSF20	Human	Homo sapiens BAFF/TNFSF13B cDNA Clone(NM_006573.3)
TNFSF13B/TNFSF20	Mouse	Mus musculus BLyS/TNFSF13B cDNA Clone
CD258/ TNFSF14	Human	Homo sapiens LIGHT/TNFSF14 transcript variant 1 cDNA Clone(NM_003807.2)

CD30 Background

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).

CD30 Related Studies

Rossi FM, et al. (2001) CD30L up-regulates CD30 and IL-4 expression by T cells. FEBS Lett. 508(3): 418-22.
Trovato M, et al. (2001) Expression of CD30 ligand and CD30 receptor in normal thyroid and benign and malignant thyroid nodules. Thyroid. 11(7): 621-8.
Ekstrom ES, et al. (2001) Presence of CD30(+) and CD30L(+) cells in human placenta and soluble CD30 levels in cord blood are independent of maternal atopy. Placenta. 22(4): 372-9.
Tang C, et al. (2008) A novel role of CD30L/CD30 signaling by T-T cell interaction in Th1 response against mycobacterial infection. J Immunol. 181(9): 6316-27.
Sun X, et al. (2008) A critical role of CD30 ligand/CD30 in controlling inflammatory bowel diseases in mice. Gastroenterology. 134(2): 447-58.
Oflazoglu E, et al. (2009) Targeting CD30/CD30L in Oncology and Autoimmune and Inflammatory Diseases.Adv Exp Med Biol. 647: 174-85.

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