**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-TNFRSF8 rabbit polyclonal antibody at 1:500 dilution.
Lane A: A431 Membrane LysateLysates/proteins at 30 ug per lane.
Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique.
Performed under reducing conditions.Predicted band size:64 kDa
Observed band size:60 kDa
(We are unsure as to the identity of these extra bands.)
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).
|Product Description||Host||Clonality||Application||Catalog# (PDF)|
|Anti-CD30 Antibody (PE)||Rabbit||Monoclonal||FCM||10777-R002-P|
|Anti-CD30 Antibody (APC)||Mouse||Monoclonal||FCM||10777-MM05-A|
|Anti-CD30 Antibody (PE)||Mouse||Monoclonal||FCM||10777-MM05-P|
|Anti-CD30 Antibody (APC)||Rabbit||Monoclonal||FCM||10777-R002-A|
|Anti-CD30 Antibody (FITC)||Mouse||Monoclonal||FCM||10777-MM05-F|