Anti-CD30 Antibody

Cat: 10777-R015
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All CD30 Reagents
CRO Services
Product recommended

All CD30 Reagents
Anti-CD30 Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-CD30 Antibody
Validated applications
ELISA,ELISA(Det)
Species reactivity
Reacts with: Human
Specificity
Human CD30
Immunogen
Recombinant Human CD30 / TNFRSF8 protein (Catalog#10777-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD30 / TNFRSF8 (rh CD30 / TNFRSF8; Catalog#10777-H08H; NP_001234.2; Met 1-Lys 379).
Source
Monoclonal Rabbit IgG Clone #015
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD30 Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  
ELISA(Det) 1:1000-1:10000 This antibody will detect Human CD30 / TNFRSF8 in ELISA pair set (Catalog: # SEK10777). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 10777-MM08).

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD30 Antibody Alternative Names
Anti-CD30 Antibody;Anti-D1S166E Antibody;Anti-Ki-1 Antibody
CD30 Background Information

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
tumor necrosis factor receptor superfamily, member 8
Research Areas
References
  • Rossi FM, et al. (2001) CD30L up-regulates CD30 and IL-4 expression by T cells. FEBS Lett. 508(3): 418-22.
  • Trovato M, et al. (2001) Expression of CD30 ligand and CD30 receptor in normal thyroid and benign and malignant thyroid nodules. Thyroid. 11(7): 621-8.
  • Ekstrom ES, et al. (2001) Presence of CD30(+) and CD30L(+) cells in human placenta and soluble CD30 levels in cord blood are independent of maternal atopy. Placenta. 22(4): 372-9.
  • Tang C, et al. (2008) A novel role of CD30L/CD30 signaling by T-T cell interaction in Th1 response against mycobacterial infection. J Immunol. 181(9): 6316-27.
  • Sun X, et al. (2008) A critical role of CD30 ligand/CD30 in controlling inflammatory bowel diseases in mice. Gastroenterology. 134(2): 447-58.
  • Oflazoglu E, et al. (2009) Targeting CD30/CD30L in Oncology and Autoimmune and Inflammatory Diseases.Adv Exp Med Biol. 647: 174-85.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD30 Antibody Rabbit Polyclonal IHC-P 101923-T08
    Anti-CD30 Antibody (PE) Rabbit Monoclonal FCM 10777-R002-P
    Anti-CD30 Antibody Mouse Monoclonal ELISA(Cap) 10777-MM08
    Anti-CD30 Antibody Mouse Monoclonal ELISA 10777-MM01
    Anti-CD30 Antibody (APC) Mouse Monoclonal FCM 10777-MM05-A
    Anti-CD30 Antibody (PE) Mouse Monoclonal FCM 10777-MM05-P
    Anti-CD30 Antibody Mouse Monoclonal ELISA 10777-MM06
    Anti-CD30 Antibody (APC) Rabbit Monoclonal FCM 10777-R002-A
    Anti-CD30 Antibody Rabbit Polyclonal ELISA 10777-RP01
    Anti-CD30 Antibody Mouse Monoclonal FCM 10777-MM05
    Anti-CD30 Antibody (FITC) Mouse Monoclonal FCM 10777-MM05-F
    Anti-CD30 Antibody Rabbit Polyclonal WB,ELISA,IHC-P 10777-RP02
    Anti-CD30 Antibody Rabbit Polyclonal ELISA 10777-T16
    info info
    添加购物车成功! 添加购物车失败!