- EGFR Signaling Pathway
- TGF-beta Signaling
- Canonical Wnt Signaling
- non-Canonical Wnt Signaling
- Notch Signaling
- p53 Pathway
- NF-kB Pathway
- Cytokine Signaling
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CD30 / TNFRSF8 Antibody Datasheet
|Order or Inquire for CD30 / TNFRSF8 Antibody product||Quality antibodies||Antibody production services|
|Detection limit is 0.00245 ng/well in ELISA|
CD30 / TNFRSF8 Antibody Product Information
Recombinant Human CD30 / TNFRSF8 protein (Catalog#10777-H08H)
|Antibody Type :||Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )|
Clone ID :
|Ig Type :||
|Formulation :||0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.|
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD30 / TNFRSF8 (rh CD30 / TNFRSF8; Catalog#10777-H08H; NP_001234.2; Met 1-Lys 379).
CD30 / TNFRSF8 Antibody Usage Guide
Human CD30 / TNFRSF8
|Direct ELISA :||This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human TNFRSF8. The detection limit for Human TNFRSF8 is approximately 0.00245 ng/well.|
|Storage :||This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
CD30 / TNFRSF8 Antibody Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|CD30/TNFRSF8||Human||CD30/Fc Protein, Recombinant||10777-H03H|
|CD30/TNFRSF8||Human||CD30 Protein, Recombinant||10777-H08H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|WB, ELISA||Mouse Monoclonal Antibody||10777-MM01|
|WB, ELISA||CD30 / TNFRSF8 Antibody||10777-RP01|
|WB, ELISA||CD30 / TNFRSF8 Antibody (Antigen Affinity Purified)||10777-RP02|
|ELISA||CD30 / TNFRSF8 Antibody||10777-R015|
CD30 / TNFRSF8 Antibody Background
Human CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily and is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. Upon ligand binding, CD30 can initiate the signal transduction that leads to the activation of NF-kappaB mediated by the adaptor proteins TRAF2 and TRAF5. As a regulator of apoptosis, CD30 induces cell death or proliferation, depending on thecell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 is expressed in embryonal carcinoma but not in seminoma, thus serving as a useful marker in distinguishing these germ cell tumors. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15.
- Ansieau, S. et al., 1996, Proc. Natl. Acad. Sci. USA.93 (24): 14053-8.
- Gedrich, RW. et al., 1996, J. Biol. Chem.271 (22): 12852-8.
- Aizawa, S. et al., 1997, J. Biol. Chem.272 (4): 2042-5.
- Schneider, C. et al., 2003, Leuk. Lymphoma. 43 (7): 1355-66.
|Tumor Necrosis Factor (TNF) Family & Receptor|