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CD28 Protein & Antibody

Cluster of Differentiation 28

CD28 Products

CD28 Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CD28 Human CD28/Fc Protein, Recombinant 11524-H02H
CD28 Human CD28 Protein, Recombinant 11524-H08H
CD28 Mouse CD28/Fc Protein, Recombinant 50103-M03H
CD28 Mouse CD28 Protein, Recombinant 50103-M08H
CD28 Human CD28 Protein, Recombinant 11524-HCCH

CD28 Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human CD28 WB, ELISA CD28 Antibody 11524-RP01
Human CD28 WB, ELISA CD28 Antibody (Antigen Affinity Purified) 11524-RP02
Human CD28 WB CD28 Antibody 11524-MM02
Human CD28 ELISA CD28 Antibody 11524-MM06
Mouse CD28 WB, ELISA CD28 Antibody (Antigen Affinity Purified) 50103-RP02

CD28 cDNA Clone

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CD28 Human Homo sapiens CD28 cDNA Clone HG11524-M
CD28 Mouse Mus musculus CD28 cDNA Clone MG50103-M
CD28 Rat Rat CD28 cDNA Clone / ORF Clone RG80302-G
CD28 Cynomolgus Cynomolgus monkey CD28 Gene cDNA Clone / ORF Clone CG90182-G
CD28 Human Human CD28 Gene cDNA Clone / ORF Clone HG11524-M-F
CD28 Human Humans CD28 Gene cDNA Clone / ORF Clone HG11524-M-N

CD86 Cell Lysate

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
CD28
WB Mouse CD28 Human Cells Transfected Lysate
(positive control) (denatured)
50103-M03HL
Mouse
CD28
WB Human CD28 Human Cells Transfected Lysate
(positive control) (denatured)
11524-H02HL
Human
CD28
WB Mouse CD28 Human Cells Transfected Lysate
(positive control) (denatured)
50103-M08HL
Mouse
CD28
WB Human CD28 / TP44 Human Cells Transfected Lysate
(positive control) (denatured)
11524-HCCHL

CD28 Related Areas

Immunology>>Adaptive Immunity>>Costimulation & Costimulatory Molecule>>CD28

Immunology>>Adaptive Immunity>>T Cell>>Regulatory T Cell / T Cell Antigen Recognition>>CD28

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>CD28

Immunology>>Cluster of Differentiation>>Dendritic Cell CD Antigen>>Dendritic Cell Co-stimulatory Molecules>>CD28

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Other>>CD28

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Regulatory T Cells / T Cell Antigen Recognition>>CD28

CD28 Alternative Names

CD28, MGC138290, Tp44 [Homo sapiens]

Cd28, CH29-189K17.3 [Mus musculus]

CD28 Background

CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.

CD28 Related Studies

  1. Keir ME, et al. (2005) The B7/CD28 costimulatory family in autoimmunity. Immunol Rev. 204: 128-43.
  2. Sansom DM, et al. (2006) The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology. Immunol Rev. 212: 131-48.
  3. Bjørgo E, et al. (2010) Novel mechanism of signaling by CD28. Immunol Lett. 129(1): 1-6.

 

 

CD28 related areas, pathways, and other information

 

 

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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