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CD28 Antibody, Rabbit PAb

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Human CD28 Antibody Product Information
Immunogen:Recombinant Human CD28 protein (Catalog#11524-H08H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Human CD28 (rh CD28; Catalog#11524-H08H; P10747-1; Met 1-Pro 152). Total IgG was purified by Protein A affinity chromatography.
Human CD28 Antibody Usage Guide
Specificity:Human CD28
Application:ELISA

ELISA: 0.5-1.0 μg/mL

This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human CD28. The detection limit for Human CD28 is approximately 0.039 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other CD28 Antibody Products
Reactivity : Human  
Application : ELISA  
    11524-RP02-200
    11524-RP02-50
    11524-RP02-100
    200 µg 
    50 µg 
    100 µg 
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    Reactivity : Human  
    Application : ELISA  
      11524-MM06-200
      11524-MM06-50
      11524-MM06-100
      200 µg 
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      Reactivity : Human  
      Application : FCM  
      • Slide 1
      11524-R007-F-100
      11524-R007-F-50
      100 Tests 
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      Reactivity : Human  
      Application : ELISA  
        11524-R007-50
        11524-R007-100
        50 µg 
        100 µg 
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        Reactivity : Mouse  
        Application : ELISA  IHC-P  
        • Slide 1
        50103-RP02-50
        50103-RP02-100
        50103-RP02-200
        50 µg 
        100 µg 
        200 µg 
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        Reactivity : Mouse  
        Application : ELISA  WB  
        • Slide 1
        50103-T48-200
        50103-T48-50
        50103-T48-100
        200 µg 
        50 µg 
        100 µg 
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        Reactivity : Mouse  
        Application : ELISA  
          50103-RP01-400
          50103-RP01-200
          50103-RP01-100
           
          200 µg 
          100 µg 
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          Reactivity : Rat  
          Application : ELISA  
            80302-T16-200
            80302-T16-100
            80302-T16-50
            200 µg 
            100 µg 
            50 µg 
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            CD28/TP44 Background

            CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.

            Human CD28/TP44 References
          • Keir ME, et al. (2005) The B7/CD28 costimulatory family in autoimmunity. Immunol Rev. 204: 128-43.
          • Sansom DM, et al. (2006) The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology. Immunol Rev. 212: 131-48.
          • Bjrgo E, et al. (2010) Novel mechanism of signaling by CD28. Immunol Lett. 129(1): 1-6.
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            Catalog: 11524-RP01-400
            List Price: 
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            All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
            Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"