Anti-CD28 Antibody

Cat: 50103-RP02
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All CD28 Reagents
Anti-CD28 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CD28 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse CD28
Recombinant Mouse CD28 protein (Catalog#50103-M08H)
Produced in rabbits immunized with purified, recombinant Mouse CD28 (rM CD28; Catalog#50103-M08H; NP_031668.3; Met 1-Lys 149). CD28 specific IgG was purified by Mouse CD28 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD28 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  
IHC-P 1:1000-1:4000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD28 Antibody (Rabbit Polyclonal antibody) Images
Mouse CD28/TP44 Immunohistochemistry(IHC) 3352
Immunochemical staining of mouse CD28 in mouse spleen with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).
CD28 Background Information

CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: IHC Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Targets   Co-stimulatory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
CD28 molecule
  • Keir ME, et al. (2005) The B7/CD28 costimulatory family in autoimmunity. Immunol Rev. 204: 128-43.
  • Sansom DM, et al. (2006) The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology. Immunol Rev. 212: 131-48.
  • Bjrgo E, et al. (2010) Novel mechanism of signaling by CD28. Immunol Lett. 129(1): 1-6.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD28 Antibody Mouse Monoclonal ELISA 80302-MM04
    Anti-CD28 Antibody Rabbit Polyclonal ELISA 80302-T16
    Anti-CD28 Antibody Rabbit Polyclonal WB,ELISA 50103-T48
    Anti-CD28 Antibody Rabbit Polyclonal ELISA 50103-RP01
    Anti-CD28 Antibody Rabbit Monoclonal ELISA,FCM 11524-R007
    Anti-CD28 Antibody (FITC) Rabbit Monoclonal FCM 11524-R007-F
    Anti-CD28 Antibody FCM,Func/A 11524-H001
    Anti-CD28 Antibody (PerCP) Rabbit Monoclonal FCM 11524-R007-C
    Anti-CD28 Antibody Rabbit Polyclonal ELISA 11524-RP01
    Anti-CD28 Antibody Rabbit Polyclonal ELISA 11524-RP02
    Anti-CD28 Antibody Mouse Monoclonal ELISA(Det) 11524-MM04
    Anti-CD28 Antibody Mouse Monoclonal ELISA,ELISA(Cap) 11524-MM06
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