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CD23 / FCER2 Antibody, Rabbit PAb, Antigen Affinity Purified

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    Mouse CD23 Antibody Product Information
    Immunogen:Recombinant Mouse CD23 / FCER2 protein (Catalog#50695-M07H)
    Clone ID:
    Ig Type:Rabbit IgG
    Concentration:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:Produced in rabbits immunized with purified, recombinant Mouse CD23 / FCER2 (rM CD23 / FCER2; Catalog#50695-M07H; P20693-1; Glu 51-Pro 331). CD23 / FCER2 specific IgG was purified by Mouse CD23 / FCER2 affinity chromatography.
    Other CD23 Antibody Products
    Reactivity: Human  
    Application: 
    • Slide 1
    10261-MM12-50
    10261-MM12-200
    10261-MM12-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: 
    • Slide 1
    10261-MM12-P-25
    10261-MM12-P-100
    25 Test 
    100 Tests 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10261-R176-50
      10261-R176-100
      50 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: 
      • Slide 1
      10261-MM20-C-25
      10261-MM20-C-100
      25 Test 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  IHC-P  
      • Slide 1
      • Slide 1
      10261-MM05-50
      10261-MM05-200
      10261-MM05-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: 
      • Slide 1
      10261-MM20-P-25
      10261-MM20-P-100
      25 Test 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: 
      • Slide 1
      10261-MM12-C-25
      10261-MM12-C-100
      25 Test 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: 
      • Slide 1
      10261-MM12-F-25
      10261-MM12-F-100
      25 Test 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10261-RP01-400
        10261-RP01-200
        10261-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart
        Reactivity: Human  
        Application: 
        • Slide 1
        10261-MM20-F-25
        10261-MM20-F-100
        25 Test 
        100 Tests 
        Add to Cart
        Reactivity: Human  
        Application: 
        • Slide 1
        10261-MM12-A-25
        10261-MM12-A-100
        25 Test 
        100 Tests 
        Add to Cart
        Reactivity: Human  
        Application: IHC-P  
        • Slide 1
        • Slide 1
        • Slide 1
        10261-R160-50
        10261-R160-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  WB  
        • Slide 1
        10261-T48-50
        10261-T48-200
        10261-T48-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        Reactivity: Human  
        Application: 
        • Slide 1
        • Slide 1
        10261-MM19-50
        10261-MM19-200
        10261-MM19-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        Reactivity: Human  
        Application: 
        • Slide 1
        10261-MM20-A-25
        10261-MM20-A-100
        25 Test 
        100 Tests 
        Add to Cart
        Reactivity: Human  
        Application: 
        • Slide 1
        10261-MM20-50
        10261-MM20-200
        10261-MM20-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: FCM  IF  ICC/IF  
        • Slide 1
        • Slide 1
        50695-R007-50
        50695-R007-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: FCM  
        • Slide 1
        • Slide 1
        50695-R007-F-25
        50695-R007-F-100
        25 Test 
        100 Tests 
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  
          50695-R011-50
          50695-R011-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: FCM  
          • Slide 1
          • Slide 1
          50695-R007-A-25
          50695-R007-A-100
          25 Test 
          100 Tests 
          Add to Cart
          Reactivity: Mouse  
          Application: FCM  
          • Slide 1
          50695-R007-C-25
          50695-R007-C-100
          25 Test 
          100 Tests 
          Add to Cart
          Reactivity: Mouse  
          Application: FCM  
          • Slide 1
          • Slide 1
          50695-R007-P-25
          50695-R007-P-100
          25 Test 
          100 Tests 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            50695-RP01-400
            50695-RP01-200
            50695-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart

            Anti-Histone H3 rabbit monoclonal antibody at 1:200 dilution

            Lane A: NIH3T3 Whole Cell Lysate

            Lane B: Hela Whole Cell Lysate

            Lysates/proteins at 30 μg per lane.

            Secondary

            Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

            Developed using the ECL technique.

            Performed under reducing conditions.

            Predicted band size:15 kDa

            Observed band size:17 kDa

            CD23/FCER2 Background

            Fc fragment of IgE, low affinity II, receptor for (CD23) or CD23 antigen is a member of the cluster of differentiation family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD23/FCER2 is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Increased levels of soluble CD23/FCER2 cause the recruitment of non-sensitised B-cells in the presentation of antigen peptides to allergen-specific B-cells, therefore increasing the production of allergen specific IgE. IgE, in turn, is known to upregulate the cellular expression of CD23 and Fc epsilon RI (high-affinity IgE receptor).

            Mouse CD23/FCER2 References
          • Aubry JP, et al. (1992) CD21 is a ligand for CD23 and regulates IgE production. Nature. 358(6386): 505-7.
          • Punnonen J, et al. (1993) Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci U S A. 90(8): 3730-4.
          • Yu P, et al. (1994) Negative feedback regulation of IgE synthesis by murine CD23. Nature. 369(6483): 753-6.
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            Catalog: 50695-RP02-50
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            Datasheet & Documentation

            All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
            Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"