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CD226/DNAM-1/PTA1  Protein, Antibody, ELISA Kit, cDNA Clone

Description: Active  
Expression host: Human Cells  
  • Slide 1
10565-H03H-50
10565-H03H-100
50 µg 
100 µg 
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Description: Active  
Expression host: Human Cells  
  • Slide 1
10565-H08H-50
10565-H08H-100
50 µg 
100 µg 
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Description: Active  
Expression host: Human Cells  
  • Slide 1
50232-M03H-50
50232-M03H-100
50 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Human Cells  
  • Slide 1
50232-M08H-50
50232-M08H-100
50 µg 
100 µg 
Add to Cart
Expression host: Human Cells  
  • Slide 1
80369-R08H-50
80369-R08H-200
50 µg 
200 µg 
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Expression host: Human Cells  
  • Slide 1
80369-R02H-50
80369-R02H-100
50 µg 
100 µg 
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CD226/DNAM-1/PTA1 Related Pathways

    CD226/DNAM-1/PTA1 Summary & Protein Information

    CD226/DNAM-1/PTA1 Background

    Gene Summary: OMIM - description for CD226 (DNAM-1):
    General information above from NCBI
    Subunit structure: Interacts with PVR and PVRL2.
    Subcellular location: Membrane; Single-pass type I membrane protein (Potential).
    Tissue specificity: Expressed by peripheral blood T-lymphocytes.
    Sequence similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains.C
    General information above from UniProt

    The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD226, also known as PTA1 or DNAM-1, is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. High rate of CD226 (Cluster of Differentiation 226) is found on the surface of natural killer cells, platelets, monocytes and a subset of T cells. CD226 have binding sites with CD112 and CD155 and mediate cellular adhesion to other cells containing its ligands.

    Immune Checkpoint
    Immune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM Antibodies
    Immune Checkpoint Proteins
    Immune Checkpoint TargetsCo-stimulatory Immune Checkpoint Targets

    CD226/DNAM-1/PTA1 Alternative Name

    CD226/DNAM-1/PTA1 Related Studies

  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"