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CD226 / DNAM-1 Antibody (PE), Rabbit MAb

  • Human CEACAM‑1/CD66a Flow Cytometry (FC) 4969
  • CD226 / DNAM-1 Antibody (PE), Rabbit MAb, Flow cytometric analysis
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Mouse CD226 Antibody Product Information
Immunogen:Recombinant Mouse CD226 / DNAM-1 protein (Catalog#50232-M08H)
Clone ID:026
Ig Type:Rabbit IgG
Concentration:10 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD226 / DNAM-1 (rM CD226 / DNAM-1; Catalog#50232-M08H; NP_848802.2; Met1-Pro254) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Mouse CD226 Antibody FC Application Image
CD226 / DNAM-1 Antibody (PE), Rabbit MAb, Flow cytometric analysis
[Click to enlarge image]
Caption:
Analysis of CD226 expression on spleen lymphocytes.
Other CD226 Antibody Products
CD226/DNAM-1/PTA1 Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD226, also known as PTA1 or DNAM-1, is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. High rate of CD226 (Cluster of Differentiation 226) is found on the surface of natural killer cells, platelets, monocytes and a subset of T cells. CD226 have binding sites with CD112 and CD155 and mediate cellular adhesion to other cells containing its ligands.

Immune Checkpoint
Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: FCM Antibodies
Immune Checkpoint Proteins
Immune Checkpoint Targets   Co-stimulatory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Mouse CD226/DNAM-1/PTA1 References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
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    Catalog: 50232-R026-P-25
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    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"