All LAMP3 reagents are produced in house and quality controlled, including 7 LAMP3 Antibody, 1 LAMP3 ELISA, 39 LAMP3 Gene, 1 LAMP3 IPKit, 2 LAMP3 Lysate, 2 LAMP3 Protein, 2 LAMP3 qPCR. All LAMP3 reagents are ready to use.
Recombinant LAMP3 proteins are expressed by HEK293 Cells with fusion tags as C-His.
LAMP3antibodies are validated with different applications, which are WB, ELISA, IHC-P, IP, ICC/IF, IF, ELISA(Det), ELISA(Cap).
LAMP3cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each LAMP3 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
LAMP3ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces.