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Human CD208 / DC-LAMP / LAMP3 ELISA Pair Set
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Human CD208 / DC-LAMP / LAMP3 ELISA Pair Set PDF Download

Catalog   Size (Price) Quantity In Stock Operation
SEK10527  

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Human CD208 / DC-LAMP / LAMP3 ELISA Pair Set

Order or Inquire for CD208 / DC-LAMP / LAMP3 ELISA Pair Set
High affinity Human CD208 / DC-LAMP / LAMP3 ELISA Pair Set
Detection limit - 31.25 pg/ml
Affordable price and 30%-80% cost saving for Bulk order
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Human CD208 / DC-LAMP / LAMP3 ELISA Pair Set Related Products & Topics

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Background

Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family. DC-LAMP and CD68 share very similar predicted structure and are the only two members of this LAMP family with a single membrane-proximal (domain II) lamp-like domain, and a region considered as a mucin-like structure rich in serines and threonines in the N-terminal portion (domain I) . DC-LAMP is highly glycosylated: the observed mass of the mature glycoprotein on SDS-PAGE is around 70–90 kDa, whereas the predicted mass for the polypeptide core is 44 kDa. The presence of DC-LAMP in the MIIC in late mature DC indicates that this may perform an important function during the processing of exogenous antigens, and might also participate in the functional remodeling of the MIIC by facilitating the translocation of MHC class II molecules to the cell surface.Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces.

 
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