Anti-CD20 Antibody

Cat: 60004-RP02
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All CD20 Reagents
Anti-CD20 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CD20 Antibody
Validated applications
Species reactivity
Reacts with: Ferret
Ferret CD20
Recombinant Ferret CD20 / MS4A1 protein (Catalog#60004-F08H)
Produced in rabbits immunized with purified, recombinant Ferret CD20 / MS4A1 (rF CD20 / MS4A1; Catalog#60004-F08H; Glu 213-Pro 297). CD20 / MS4A1 specific IgG was purified by Ferret CD20 / MS4A1 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD20 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  
IHC-P 1:5000-1:20000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD20 Antibody (Rabbit Polyclonal antibody) Images
Ferret CD20/MS4A1  Immunohistochemistry(IHC) 4777
Immunochemical staining of ferret CD20 in ferret spleen with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).
Ferret CD20/MS4A1  Immunohistochemistry(IHC) 4778
Immunochemical staining of ferret CD20 in ferret colon with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).
CD20 Background Information

CD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20 / MS4A1 is expressed on all stages of B cell development except the first and last. CD20 / MS4A1 is present from pre-pre B cells through memory cells, but not on either pro-B cells or plasma cells. It is a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. CD20 / MS4A1may be involved in the regulation of B-cell activation and proliferation. Defects in CD20 / MS4A1 are the cause of immunodeficiency common variable type 5(CVID5). CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
membrane-spanning 4-domains, subfamily A, member 1
  • Tedder TF, et al. (1988) Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes. Proc Natl Acad Sci. 85(1): 208-12.
  • Cragg MS, et al. (2005) The biology of CD20 and its potential as a target for mAb therapy. Curr Dir Autoimmun. 8: 140-74..
  • Polyak MJ, et al. (2003) A cholesterol-dependent CD20 epitope detected by the FMC7 antibody. Leukemia. 17(7): 1384-9.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD20 Antibody Rabbit Monoclonal ELISA 60004-R071
    Anti-CD20 Antibody Rabbit Polyclonal ELISA 60004-RP01
    Anti-CD20 Antibody (FITC) Rabbit Monoclonal FCM 11007-R001-F
    Anti-CD20 Antibody Rabbit Polyclonal WB,ELISA,IHC-P 11007-T56
    Anti-CD20 Antibody Rabbit Monoclonal FCM 11007-R001
    Anti-CD20 Antibody (PerCP) Rabbit Monoclonal FCM 11007-R001-C
    Anti-CD20 Antibody Rabbit Polyclonal WB,ELISA 11007-T48
    Anti-CD20 Antibody Mouse Monoclonal IHC-P 11007-MM03
    Anti-CD20 Antibody (APC) Rabbit Monoclonal FCM 11007-R001-A
    Anti-CD20 Antibody Rabbit Polyclonal ELISA 11007-RP01
    Anti-CD20 Antibody Mouse Monoclonal ELISA 11007-MM01
    Anti-CD20 Antibody (PE) Rabbit Monoclonal FCM 11007-R001-P
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