CD1d Protein

Cluster of Differentiation 1d

CD1d Products

CD1d Protein, Recombinant

Molecule	Species	Description	Cat. No
CD1d	Human	CD1d Protein, Recombinant	11009-H08H
CD1d	Mouse	CD1d/Fc Protein, Recombinant	50188-M03H
CD1d	Mouse	CD1d Protein, Recombinant	50188-M08H

CD1d cDNA Clone

Molecule	Species	Description	Cat. No
CD1d	Human	Homo sapiens CD1d cDNA Clone(NM_001766.3)	HG11009-M
CD1d	Mouse	Mus musculus CD1d1 cDNA Clone	MG50188-M

CD1d Related Areas

Immunology>>Adaptive Immunity>>Major Histocompatibility Complex>>CD1d

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>T Cell Antigen Recognition>>CD1d

CD1d Alternative Names

CD1D, CD1A, MGC34622, R3 [Homo sapiens]

Cd1d, Cd1d1, AI747460, CD1.1, Cd1a, Ly-38 [Mus musculus]

CD1d Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 1 (CD1) is a member of CD system. It's a family of glycoproteins expressed on the surface of various human antigen- presenting cells which are implicated in the presentation of lipid antigens to T-cells. Due to the different lipid anchoring, the CD1 family is classified into two groups: group1 (CD1a-c) and group2 (CD1d). CD1d with lipid antigens activate NK T-cells which rapidly produce Th1 and Th2 cytokines after been activated.

CD1d Related Studies

1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125–35.
3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
4. Joyce S. (2001) CD1d and natural T cells: how their properties jump-start the immune system. Cell Mol Life Sci. 58 (3): 442–69.