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CD19 Antibody, Mouse MAb

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    Human CD19 Antibody Product Information
    Immunogen:Recombinant Human CD19 Protein (Catalog #11880-H08H)
    Clone ID:05
    Ig Type:Mouse IgG1
    Concentration:
    Formulation:0.2 μm filtered solution in PBS
    Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD19 (rh CD19; Catalog#11880-H08H; Met 1-Lys 291; P15391). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
    Other CD19 Antibody Products
    Reactivity: Human  
    Application: ELISA  IP  
    • Slide 1
    11880-R410-50
    11880-R410-100
    50 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  IP  
    • Slide 1
    11880-R303-50
    11880-R303-100
    50 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      11880-RP01-200
      11880-RP01-100
      11880-RP01-400
      200 µg 
      100 µg 
       
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      11880-MM17-F-100
      11880-MM17-F-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      11880-MM17-P-100
      11880-MM17-P-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Human  
      Application: IHC-P  
      • Slide 1
      • Slide 1
      11880-R109-100
      11880-R109-50
      100 µg 
      50 µg 
      Add to Cart
      CD19 Background

      The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell coreceptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.

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      Human CD19 References
    • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
    • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
    • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
    • Carter RH, et al. (1992) CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science. 256 (5053): 105-7.
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      Catalog: 11880-MM05-50
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      Datasheet & Documentation

      All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"