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> CD16 Protein & Antibody (FCGR3) CD16 Protein & Antibody (FCGR3)
Cluster of differentiation 16 (Fc gamma Receptor III)
CD16 Alternative Names
CD16, FCGR3A, FCG3, FCGR3, Fc γ RIII, Fc gamma RIII, FCGRIII, FCRIII, FCRIIIA, FCRIIIB, IGFR3, FCR-10 [Homo sapiens]
CD16; CD16-2, Fcgr3, Fcgr3a, Fcgr4, FcRIII, FcgRIV, FcgammaRIV [Mus musculus]
CD16 Protein & Antibody
Sino Biological offers a comprehensive set of research tools (proteins, antibodies) for Cluster of differentiation (CD) related research. We offer CD proteins from human and mouse. Our antibody products include mouse monoclonal and rabbit polyclonal antibodies for application such as ELISA, Western Blotting, IHC, etc. All of our antibodies were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.
CD16 Protein, Recombinant
10389-H27H-B: Measured by its ability to bind recombinant human IgG1 in a functional ELISA.
10389-H27H1-B: Measured by its ability to bind recombinant human IgG1 in a functional ELISA.
CD16 Antibody
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CD16 | Mouse | CD16 Protein, Recombinant | 50326-M08H |
| CD16 | Cynomolgus | CD16 Protein, Recombinant | 90013-C08H |
| CD16 | Cynomolgus | CD16 Protein, Recombinant, with AVI Tag | 90013-C27H |
| Human CD16a |
ELISA | Mouse Monoclonal Antibody | 10389-MM02 |
| Human CD16a |
ELISA | Mouse Monoclonal Antibody | 10389-MM03 |
| Human CD16a |
WB, ELISA | CD16a Antibody, Rabbit PAb | 10389-RP01 |
| Human CD16a |
WB, ELISA | CD16a Antibody, Rabbit PAb (Antigen Affinity Purified) | 10389-RP02 |
| Human CD16b |
ELISA | Mouse Monoclonal Antibody | 11046-MM01 |
| Human CD16b |
WB | Mouse Monoclonal Antibody | 11046-MM04 |
| Human CD16b |
WB | Mouse Monoclonal Antibody | 11046-MM09 |
| Human CD16b |
WB, ELISA | Rabbit Polyclonal Antibody | 11046-RP01 |
| Human CD16b |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 11046-RP02 |
| Mouse CD16-2 |
WB, ELISA | CD16-2 Antibody, Rabbit MAb | 50036-R012 |
| Mouse CD16-2 |
WB, ELISA | Rabbit Polyclonal Antibody | 50036-RP01 |
| Mouse CD16-2 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 50036-RP02 |
| Cynomolgus CD16-2 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 90013-RP02 |
CD16 Related Areas
Cancer>>Cancer Stem Cell (CSC)>>CD16
Immunology>>Cluster of Differentiation>>Dendritic Cell CD Antigen>>Dendritic Cell Lineage Markers>>CD16
Immunology>>Cluster of Differentiation>>Granulocyte CD Antigen>>Granulocyte Markers / Neutrophils>>CD16
Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Macrophage Markers / Monocyte Markers>>CD16
Immunology>>Cluster of Differentiation>>Natural Killer (NK) Cell CD Antigen>>CD16
Immunology>>Fc Receptor>>CD16
CD16 Related Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| CD32 | Mouse | CD32 Protein, Recombinant |
| CD32a | Human | CD32a/FCGR2A/Fc Protein, Recombinant |
| CD32a | Human | CD32a Protein, Recombinant |
| CD32a | Human | CD32a Protein, Recombinant |
| CD32b | Human | CD32b Protein, Recombinant |
| CD89 | Human | CD89 Protein, Recombinant |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! |
| Mouse CD32 |
ELISA | Rabbit Polyclonal Antibody |
| Mouse CD32 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Human CD32a |
ELISA | Mouse Monoclonal Antibody |
| Human CD32a |
ELISA | Mouse Monoclonal Antibody |
| Human CD32b |
WB, ELISA | Mouse Monoclonal Antibody |
| Human CD32b |
ELISA | Rabbit Polyclonal Antibody |
| Human CD32b |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| CD16 | Cynomolgus | Cynomolgus monkey CD16/FCGR3 cDNA Clone / ORF Clone |
| CD16a | Human | Homo sapiens CD16a transcript variant 5 cDNA Clone(NM_001127596.1) |
| CD16a | Rat | Rattus norvegicus CD16a cDNA Clone |
| CD32 | Mouse | Mus musculus CD32 cDNA Clone |
| CD32a | Human | Homo sapiens CD32a transcript variant 1 cDNA Clone(NM_001136219.1) |
| CD32a | Rat | Rattus norvegicus CD32a/FCGR2A cDNA Clone |
| CD32b | Human | Homo sapiens CD32b transcript variant 3 cDNA Clone(NM_001002274.1) |
| CD32b | Human | Homo sapiens CD32b transcript variant 2 cDNA Clone(NM_001002273.1) |
| CD32b | Rat | Rattus norvegicus CD32b/FCGR2B cDNA Clone |
| CD64 | Human | Homo sapiens CD64 cDNA Clone(NM_000566.3) |
| CD64 | Mouse | Mus musculus CD64/FCGR1 cDNA Clone |
| CD64 | Rat | Rattus norvegicus CD64/FCGR1 cDNA Clone |
| CD89 | Human | Homo sapiens CD89/FCAR transcript variant 1 cDNA Clone(NM_002000.2) |
| CD89 | Rat | Rattus norvegicus CD89/FCAR cDNA Clone |
CD16 Background
Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.
CD16 Related Studies
- Edberg JC, et al. (2002) Genetic linkage and association of Fcgamma receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus. Arthritis Rheum. 46(8): 2132-40.
- Li P, et al. (2002) Recombinant CD16A-Ig forms a homodimer and cross-blocks the ligand binding functions of neutrophil and monocyte Fcgamma receptors. Mol Immunol. 38(7): 527-38.
- Li P, et al. (2007) Affinity and kinetic analysis of Fcgamma receptor IIIa (CD16a) binding to IgG ligands. J Biol Chem. 282(9): 6210-21.
