CD157 Protein & Antibody (BST1)

Cluster of Differentiation 157 (Bone marrow Sromal cell antigen 1)

CD157 Products

CD157 Protein, Recombinant

Molecule	Species	Description	Cat. No
CD157/BST1	Human	CD157/BST1 Protein, Recombinant	10060-H08H
CD157/BST1	Mouse	CD157/BST1 Protein, Recombinant	50319-M08H

CD157 Antibody

Molecule	Application	Description	Cat. No
Humam CD157/BST1	WB, ELISA	Mouse Monoclonal Antibody	10060-MM05
Humam CD157/BST1	WB, ELISA	CD157 / BST1 Antibody	10060-R029
Humam CD157/BST1	WB, ELISA	Rabbit Monoclonal Antibody	10060-RP01
Humam CD157/BST1	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10060-RP02
Mouse CD157/BST1	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	50319-RP02

CD157 ELISA Kit

Molecule	Application	Description	Cat. No
Human CD157/BST1	ELISA	CD157/BST1 ELISA Kit	SEK10060

CD157 cDNA Clone

Molecule	Species	Description	Cat. No
CD157/BST1	Human	Homo sapiens CD157/BST1 cDNA Clone(NM_004334.2)	HG10060-M
CD157/BST1	Mouse	Mus musculus CD157/BST1 cDNA Clone	MG50319-M
CD157/BST1	Rat	BST1 cDNA Clone / ORF Clone	RG80351-G

CD157 Related Areas

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>CD157/BST1

CD157 Alternative Names

CD157, BST1 [Homo sapiens]

CD157, Bst1, A530073F09, BP-3, Bp3, Bsta1, Ly65 [Mus musculus]

CD157 Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD157, also known as ADP-ribosyl cyclase 2, is an ectoenzyme sharing several characteristics with ADP-ribosyl cyclase CD38. CD157 was originally identified as a bone marrow stromal cell molecule (BST-1) with a glycosylphosphatidylinositol (GPI) anchor to bind to the cell surface. CD157 is prevalently expressed by cells of the myeloid lineage. CD157 could act as a receptor with signal transduction capability. Further, it regulates calcium homeostasis and promotes polarization in neutrophils and mediates superoxide (O₂₋) production in the human U937 myeloid line.

CD157 Related Studies

1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125–35.
3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
4. Malavasi F, et al. (2006) CD38 and CD157 as Receptors of the Immune System: A Bridge Between Innate and Adaptive Immunity. Molecular Medicine. 12 (11-12): 334–41.
5. Ortolan E, et al. (2002) CD157, the janus of CD38 but with a unique personality. Cell Biochemistry and Function. 20 (4): 309-22.