Anti-CD157 Antibody

Cat: 10060-RP01
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All CD157 Reagents
Anti-CD157 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CD157 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human CD157
Immunogen
Recombinant Human BST-1 protein (Catalog#10060-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human BST-1 / CD157 (rhBST-1; Catalog#10060-H08H; NP_004325.2; Met 1-Lys 292). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD157 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD157 Antibody Alternative Names
Anti-CD157 Antibody
CD157 Background Information

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD157, also known as ADP-ribosyl cyclase 2, is an ectoenzyme sharing several characteristics with ADP-ribosyl cyclase CD38. CD157 was originally identified as a bone marrow stromal cell molecule (BST-1) with a glycosylphosphatidylinositol (GPI) anchor to bind to the cell surface. CD157 is prevalently expressed by cells of the myeloid lineage. CD157 could act as a receptor with signal transduction capability. Further, it regulates calcium homeostasis and promotes polarization in neutrophils and mediates superoxide (O2−) production in the human U937 myeloid line.

Full Name
bone marrow stromal cell antigen 1
References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Malavasi F, et al. (2006) CD38 and CD157 as Receptors of the Immune System: A Bridge Between Innate and Adaptive Immunity. Molecular Medicine. 12 (11-12): 334-41.
  • Ortolan E, et al. (2002) CD157, the janus of CD38 but with a unique personality. Cell Biochemistry and Function. 20 (4): 309-22.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD157 Antibody Rabbit Polyclonal ELISA 80351-RP01
    Anti-CD157 Antibody Rabbit Polyclonal ELISA,IHC-P 80351-RP02
    Anti-CD157 Antibody Rabbit Monoclonal ELISA(Cap) 50319-R213
    Anti-CD157 Antibody Rabbit Polyclonal WB,ELISA,IP 50319-RP02
    Anti-CD157 Antibody (APC) Mouse Monoclonal FCM 10060-MM19-A
    Anti-CD157 Antibody Mouse Monoclonal ELISA,ELISA(Cap) 10060-MM05
    Anti-CD157 Antibody Mouse Monoclonal FCM 10060-MM19
    Anti-CD157 Antibody (FITC) Mouse Monoclonal FCM 10060-MM19-F
    Anti-CD157 Antibody (PE) Mouse Monoclonal FCM 10060-MM19-P
    Anti-CD157 Antibody Mouse Monoclonal FCM 10060-MM10
    Anti-CD157 Antibody (FITC) Mouse Monoclonal FCM 10060-MM10-F
    Anti-CD157 Antibody (PE) Mouse Monoclonal FCM 10060-MM10-P
    Anti-CD157 Antibody (APC) Mouse Monoclonal FCM 10060-MM10-A
    Anti-CD157 Antibody Rabbit Monoclonal ELISA 10060-R029
    Anti-CD157 Antibody Rabbit Polyclonal ELISA 10060-RP02
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