CD155 Protein & Antibody (PVR, Necl-5)

Cluster of Differentiation 155 (Poliovirus Receptor, Nectin-like protein 5)

CD155 Protein & Antibody Products

CD155 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CD155	Human	CD155/Fc Protein, Recombinant	10109-H02H
CD155	Human	CD155 Protein, Recombinant	10109-H08H
CD155	Human	CD155 Protein, Recombinant	10109-HCCH
CD155	Mouse	CD155/Fc Protein, Recombinant	50259-M03H
CD155	Mouse	CD155 Protein, Recombinant	50259-M08H
CD155	Rat	CD155 Protein, Recombinant	80007-R08H
CD155	Cynomolgus	CD155 Protein, Recombinant	90005-C08H

10109-H02H: Immobilized human DNAM1 at 2 μg/ml (100 μl/well) can bind human CD155-Fc with a linear ranger of 0.032 - 0.8 μg/ml. Measured by its binding ability in a functional ELISA.

10109-H08H: Immobilized human CD155 at 2 μg/ml (100 μl/well) can bind human DNAM1 with a linear ranger of 1.28 - 32 ng/ml. Measured by its binding ability in a functional ELISA.

10109-HCCH: Measure by its ability to bind with recombinant human DNAM1/CD226

50259-M03H: Immobilized mouse DNAM1 at 2 µg/ml (100 µl/well) can bind mouse CD155 with a linear ranger of 6.4-160 ng/ml.Measured by its binding ability in a functional ELISA.

50259-M08H: Immobilized recombinant mouse CD226/DNAM-1 at 1 µg/ml (100µl /well) can bind recombinant mouse CD155/PVR with a linear range of 0.78-100 ng/ml.Measured by its ability to bind recombinant mouse CD226/DNAM-1.

80007-R08H: Immobilized rat CD155 at 20 µg/ml (100 µl/well) can bind mouse CD226 with a linear ranger of 6.4-160 ng/ml.Measured by its ability to bind recombinant mouse CD226/DNAM-1.

90005-C08H: Immobilized cynomolgus CD155 at 2 µg/ml (100 µl/well) can bind human CD226 with a linear ranger of 1.28-32ng/ml.Measured by its ability to bind recombinant mouse CD226/DNAM-1.

CD155 Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CD155	WB, ELISA	Mouse Monoclonal Antibody	10109-MM01
Human CD155	WB, ELISA	CD155 / PVR Antibody ( FITC )	10109-MM09-F
Human CD155	WB, ELISA	CD155 Antibody, Mouse Mab	10109-MM11
Human CD155	WB, ELISA	CD155 Antibody, Rabbit MAb	10109-R114
Human CD155	WB, ELISA	CD155 Antibody, Rabbit PAb	10109-RP01
Human CD155	WB, ELISA	CD155 Antibody, Rabbit PAb (Antigen Affinity Purified)	10109-RP02
Mouse CD155	ELISA	Rabbit Monoclonal Antibody	50259-R001
Mouse CD155	FCM	CD155 / PVR Antibody ( FITC )	50259-R305-F
Mouse CD155	WB, ELISA	CD155 / PVR Antibody	50259-R501
Mouse CD155	WB, ELISA	Rabbit Polyclonal Antibody	50259-RP01
Mouse CD155	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	50259-RP02
Rat CD155	WB, ELISA	CD155 Antibody, Mouse Mab	80007-MM06
Rat CD155	WB, ELISA	CD155 Antibody, Rabbit PAb	80007-RP01
Rat CD155	WB, ELISA	CD155 Antibody, Rabbit PAb (Antigen Affinity Purified)	80007-RP02
Cynomolgus CD155	WB, ELISA	CD155 Antibody, Rabbit PAb	90005-RP01
Cynomolgus CD155	WB, ELISA	CD155 Antibody, Rabbit PAb (Antigen Affinity Purified)	90005-RP02
Cynomolgus CD155	WB, ELISA	CD155 Antibody, Mouse MAb	90005-MM06

CD155 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CD155	Human	CD155/PVR transcript variant 1 cDNA Clone / ORF Clone	HG10109-M
CD155	Mouse	CD155/PVR cDNA Clone / ORF Clone	MG50259-M
CD155	Rat	CD155/PVR cDNA Clone / ORF Clone	RG80007-G
CD155	Cynomolgus	CD155/PVR cDNA Clone / ORF Clone	CG90005-G

CD155 Alternative Names

CD155, PVR, HVED, NECL5, Necl-5, PVS, TAGE4 [Homo sapiens];

CD155, Pvr, 3830421F03Rik, D7Ertd458e, HVED, PVS, Taa1, Tage4, mE4, necl-5 [Mus musculus]

CD155 Related Areas

Immunology>>Innate Immunity>>Natural Killer Cell (NK Cell)>>CD155

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Macrophage Markers / Monocyte Markers>>CD155

CD155 Background

CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.

CD155 Related Studies

Freistadt MS, et al. (2000) Hematopoietic cells from CD155-transgenic mice express CD155 and support poliovirus replication ex vivo. Microb Pathog. 29(4): 203-12.
Sato T, et al. (2004) Involvement of heterophilic trans-interaction of Necl-5/Tage4/PVR/CD155 with nectin-3 in formation of nectin- and cadherin-based adherens junctions. Genes Cells. 9(9): 791-9.
Kakunaga S, et al. (2004) Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling. J Biol Chem. 279(35): 36419-25.
Sato T, et al. (2005) Common signaling pathway is used by the trans-interaction of Necl-5/Tage4/PVR/CD155 and nectin, and of nectin and nectin during the formation of cell-cell adhesion. Cancer Sci. 96(9): 578-89.
Minami Y, et al. (2007) Involvement of up-regulated Necl-5/Tage4/PVR/CD155 in the loss of contact inhibition in transformed NIH3T3 cells. Biochem Biophys Res Commun. 352(4): 856-60.

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