All SLAM / CD150 reagents are produced in house and quality controlled, including 8 SLAM / CD150 Antibody, 2 SLAM / CD150 ELISA, 26 SLAM / CD150 Gene, 3 SLAM / CD150 Lysate, 3 SLAM / CD150 Protein, 2 SLAM / CD150 qPCR. All SLAM / CD150 reagents are ready to use.
Recombinant SLAM / CD150 proteins are expressed by HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc.
SLAM / CD150antibodies are validated with different applications, which are ELISA(Cap), ELISA, ELISA(Det), IHC-P.
SLAM / CD150cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each SLAM / CD150 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
SLAM / CD150ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with an activated B cell phenotype. Additionally, it is the immune cell receptor for measles virus (MV). As a self-ligand, CD150 performs diverse immunologic functions including T/B-cell costimulation, induction of IFN-&gamma in Th1 T-cell clones, redirection of Th2 clones to a Th1 or Th0 phenotype, and inhibition of apoptosis in B cells. Furthermore, CD150 was shown to be the second receptor for measles virus in addition to CD46, and the distribution of SLAM on various cell lines is consistent with their susceptibility to clinical isolates of measles virus.