All CD147 reagents are produced in house and quality controlled, including 15 CD147 Antibody, 2 CD147 ELISA, 41 CD147 Gene, 1 CD147 IPKit, 5 CD147 Lysate, 5 CD147 Protein, 2 CD147 qPCR. All CD147 reagents are ready to use.
Recombinant CD147 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His, C-cleavage, C-human IgG1-Fc & His.
CD147antibodies are validated with different applications, which are ELISA, IHC-P, ELISA(Det), FCM, ELISA(Cap), WB, ICC/IF, IF, IHC-Fr, IP.
CD147cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD147 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CD147ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.