Anti-CD147 Antibody (FITC)

Cat: 10186-R125F
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All CD147 Reagents
Anti-CD147 Antibody (FITC) (Rabbit Monoclonal antibody) General Information
Product name
Anti-CD147 Antibody (FITC)
Validated applications
Species reactivity
Reacts with: Human
Human CD147
Recombinant Human CD147 protein (Catalog#10186-H08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD147 / Basigin (rh CD147; Catalog#10186-H08H; NP_940991.1; Met 1-His 205) and conjugated with FITC under optimum conditions, the unreacted FITC was removed .
Monoclonal Rabbit IgG Clone #125
Protein A
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
10 μl/Test, 0.1 mg/ml
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Anti-CD147 Antibody (FITC) (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ICC-IF 1-10 μg/mL  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD147 Antibody (FITC) (Rabbit Monoclonal antibody) Images
Human CD147/EMMPRIN/Basigin Flow Cytometry (FC) 2536
Profile of peripheral blood lymphocytes analyzed by flow cytometry. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable lymphocytes.
Human CD147/EMMPRIN/Basigin Immunofluorescence(IF) 2979
Immunofluorescence staining of human CD147 in HeLa cells with rabbit monoclonal antibody (5 µg/mL). The image showing membrane staining of HeLa cells. Primary antibody (FITC conjugated) was incubated for 1 hour at 37℃.
Anti-CD147 Antibody (FITC) Alternative Names
Anti-5F7 Antibody;Anti-Basigin Antibody;Anti-CD147 Antibody;Anti-EMMPRIN Antibody;Anti-M6 Antibody;Anti-OK Antibody;Anti-TCSF Antibody
CD147 Background Information

CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.

Full Name
basigin (Ok blood group)
  • Tang Y, et al. (2004) Tumor-stroma interaction: positive feedback regulation of extracellular matrix metalloproteinase inducer (EMMPRIN) expression and matrix metalloproteinase-dependent generation of soluble EMMPRIN. Mol Cancer Res. 2(2): 73-80.
  • Wilson MC, et al. (2005) Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70). J Biol Chem. 280(29): 27213-21.
  • Curtin KD, et al. (2005) Basigin (EMMPRIN/CD147) interacts with integrin to affect cellular architecture. J Cell Sci. 118(Pt 12): 2649-60.
  • Zhu H, et al. (2009) A novel antibody fragment targeting HAb18G/CD147 with cytotoxicity and decreased immunogenicity. Cancer Biol Ther. 8(11): 1035-44. Zhu H, et al. (2009) A novel antibody fragment targeting HAb18G/CD147 with cytotoxicity and decreased immunogenicity. Cancer Biol Ther. 8(11): 1035-44.
  • Seizer P, et al. (2009) EMMPRIN (CD147) is a novel receptor for platelet GPVI and mediates platelet rolling via GPVI-EMMPRIN interaction. Thromb Haemost. 101(4): 682-6.
  • Moonsom S, et al. (2010) A Competitive ELISA for Quantifying Serum CD147: Reduction of Soluble CD147 Levels in Cancer Patient Sera. Hybridoma (Larchmt). 29(1): 45-52.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD147 Antibody Rabbit Monoclonal ELISA,ICC/IF,IF 50332-R041
    Anti-CD147 Antibody Rabbit Polyclonal ELISA 50332-RP01
    Anti-CD147 Antibody Rabbit Polyclonal ELISA 50332-RP02
    Anti-CD147 Antibody (PE) Mouse Monoclonal FCM 10186-MM08-P
    Anti-CD147 Antibody Rabbit Monoclonal ELISA(Det) 10186-R118
    Anti-CD147 Antibody (FITC) Rabbit Monoclonal FCM,ICC/IF,IF 10186-R125-F
    Anti-CD147 Antibody (PE) Rabbit Monoclonal FCM 10186-R125-P
    Anti-CD147 Antibody Rabbit Polyclonal ELISA,IHC-P 10186-RP02
    Anti-CD147 Antibody Mouse Monoclonal ELISA,ELISA(Cap),IHC-P 10186-MM05
    Anti-CD147 Antibody (APC) Mouse Monoclonal FCM 10186-MM08-A
    Anti-CD147 Antibody Rabbit Monoclonal WB,ELISA,IHC-P,IHC-Fr,FCM,ICC/IF,IF,IP 10186-R125
    Anti-CD147 Antibody Mouse Monoclonal ELISA,FCM,ICC/IF,IF 10186-MM08
    Anti-CD147 Antibody (FITC) Mouse Monoclonal FCM,ICC/IF,IF 10186-MM08-F
    Anti-CD147 Antibody (APC) Rabbit Monoclonal FCM 10186-R125-A
    Anti-CD147 Antibody Rabbit Polyclonal WB,ELISA 10186-RP01
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