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CD147 / EMMPRIN / Basigin Antibody, Mouse MAb
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CD147 / EMMPRIN / Basigin Antibody, Mouse MAb PDF Download

Catalog   Size (Price) Quantity In Stock Operation
10186-MM05  

YES   
 

Primary antibody | Secondary antibody | Tag antibody | Isotype control antibody | Loading control antibody | Antibody Purification

CD147 / Basigin / BSG Antibody

  Order or Inquire for CD147 Antibody product Quality antibodies Antibody production services
  Detection limit is 1 ng/lane in WB
  Detection limit is 0.0195 ng/well in ELISA
 

CD147 / Basigin / BSG Antibody Product Information

Immunogen :

Recombinant human CD147 protein ( Catalog#10186-H08H )

Antibody Type : Mouse Monoclonal Antibody ( Mouse mAb Service Platform )

Clone ID :

6H11C1

Ig Type :

Mouse IgG2a

Formulation : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
Preparation :

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, human cell-derived, recombinant human CD147. ( rh CD147 ; Catalog#10186-H08H ; NP_940991.1 ; Met 1- His 205 ). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

CD147 / Basigin / BSG Antibody Usage Guide

Specificity :

Human CD147 / Basigin / BSG

  No cross-reactivity with human cell lysate ( 293 cell line ) in WB and ELISA.
Immunochemistry :

IHC-P: 5-20 μg/mL

 

CD147-esophagus immunohistochemistry    CD147-gastric-cancer immunohistochemistry

Immunochemical staining of human CD147 in human esophagus with mouse monoclonal antibody (10 µg/mL, formalin-fixed paraffin embedded sections). The image showing membrane staining of squamous epithelium cell. Immunochemical staining of human CD147 in human gastric cancer with mouse monoclonal antibody (10 µg/mL, formalin-fixed paraffin embedded sections). The image showing membrane staining of epithelium cell.

 

CD147-stomach immunohistochemistry    

Immunochemical staining of human CD147 in human stomach with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). The image showing membrane staining of epithelium cell.  
Direct ELISA : This antibody can be used at 0.5 - 1μg/mL with the appropriate secondary reagents to detect human CD147. The detection limit for human CD147 is 0.0195 ng/well
Storage : This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

CD147 / Basigin / BSG Antibody Related Products & Topics

Related Areas:

Enzyme>>Protease & Regulator>>Metalloprotease & Regulator>>CD147/EMMPRIN

Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hemangioblast>>Endothelial Cell Marker>>CD147/EMMPRIN

Cancer>>Cancer Biomarkers>>CD147/EMMPRIN

Immunology>>Adaptive Immunity>>T Cell>>T Cell Migration/Adhesion>>CD147/EMMPRIN

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>CD147/EMMPRIN

Immunology>>Cluster of Differentiation>>Dendritic Cell CD Antigen>>Dendritic Cell Adhesion>>CD147/EMMPRIN

Immunology>>Cluster of Differentiation>>Granulocyte CD Antigen>>Basophils / Eosinophils / Granulocyte Markers / Neutrophils>>CD147/EMMPRIN

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Monocyte Markers>>CD147/EMMPRIN

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>T Cell Migration/Adhesion>>CD147/EMMPRIN

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CD147/EMMPRIN Human CD147/EMMPRIN/Fc Protein, Recombinant 10186-H02H
CD147/EMMPRIN Human CD147/EMMPRIN Protein, Recombinant 10186-H08H
CD147/EMMPRIN Human CD147/EMMPRIN Protein, Recombinant 10186-HCCH
CD147/EMMPRIN Mouse CD147/EMMPRIN/Fc Protein, Recombinant 50332-M03H
CD147/EMMPRIN Mouse CD147/EMMPRIN Protein, Recombinant 50332-M08H

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
CD147/EMMPRIN
WB, ELISA Mouse Monoclonal Antibody 10186-MM05
Human
CD147/EMMPRIN
ELISA, ICC/IF, IF CD147 / EMMPRIN / Basigin Antibody 10186-MM08
Human
CD147/EMMPRIN
FCM CD147 / EMMPRIN / Basigin Antibody ( FITC ) 10186-MM08-F
Human
CD147/EMMPRIN
WB, ELISA, IHC Rabbit Monoclonal Antibody 10186-R125
Human
CD147/EMMPRIN
Flow Cytometry CD147/EMMPRIN Antibody, Rabbit MAb 10186-R125F
Human
CD147/EMMPRIN
WB, ELISA Rabbit Polyclonal Antibody 10186-RP01
Human
CD147/EMMPRIN
WB, ELISA Rabbit Polyclonal Antibody 10186-RP02
Mouse
CD147/EMMPRIN
WB, ELISA CD147/EMMPRIN Antibody, Rabbit MAb 50332-R041
Mouse
CD147/EMMPRIN
WB, ELISA Rabbit Polyclonal Antibody 50332-RP01
Mouse
CD147/EMMPRIN
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 50332-RP02

CD147 / Basigin / BSG Antibody Background

CD147, also known as Basigin, BSG, and EMMPRIN, is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation, and tumor progression. Enriched on the plasma memebrane of many human cancer (breast cancer, lymphoma, oral squamous cell carcinoma, glioma, melanoma, lung, bladder and kidney carcinomas ) cells, CD147 induces the production and release of matrix metalloproteinases in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction.

References

  1. Kanekura, T. et al., 1991, Cell. Struct. Funct. 16 : 23-30.
  2. Muramatsu ,T. et al., 2003, Histol Histopathol. 18 : 981-7.
  3. Jin-Ming Yang. et al., 2006, J. Biol. Chem. 281: 9719-27.
  4. Hakuma, N. et al., 2007, Oncology. 72 : 197-204.
  5. Zheng HC. et al., 2006, Br. J. Cancer. 95 : 1371-8.
  6. Yurchenko,V. et al., 2002, J. Biol. Chem. 277 : 22959-65.
 

 

CD147 (EMMPRIN) related areas, pathways, and other information

 

Primary Antibody Products

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"