CD14 Protein & Antibody

Cluster of Differentiation 14

CD14 Products

CD14 Protein, Recombinant

Molecule	Species	Description	Cat. No
CD14	Human	CD14/Fc Protein, Recombinant	10073-H01H
CD14	Human	CD14 Protein, Recombinant	10073-H08H
CD14	Mouse	CD14/Fc Protein, Recombinant	50023-M03H
CD14	Mouse	CD14 Protein, Recombinant	50023-M08H

CD14 Antibody

Molecule	Application	Description	Cat. No
Mouse CD14	WB, ELISA	Rabbit Monoclonal Antibody	50023-R002
Mouse CD14	WB, ELISA	Rabbit Polyclonal Antibody	50023-RP01
Mouse CD14	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	50023-RP02

CD14 Elisa Pair Set

Molecule	Application	Description	Cat. No
Mouse CD14	ELISA	CD14 ELISA Kit	SEK50023

CD14 cDNA Clone

Molecule	Species	Description	Cat. No
CD14	Human	Homo sapiens CD14 transcript variant 1 cDNA Clone(NM_000591.2)	HG10073-M
CD14	Mouse	Mus musculus CD14 cDNA Clone	MG50023-M

CD14 Related Areas

Immunology>>Cluster of Differentiation>>Dendritic Cell CD Antigen>>Dendritic Cell Lineage Markers>>CD14

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Monocyte Markers>>CD14

CD14 Alternative Names

CD14, CD14 antigen, monocyte differentiation antigen CD14

CD14 Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.

CD14 Related Studies

1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125–35.
3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
4. SD Wright, et al. (1990) CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science. 249 (4975): 1431-3.