CD14 (Protein | Antibody | cDNA Clone | ELISA Kit)

All CD14 reagents are produced in house and quality controlled, including 39 CD14 Antibody, 1 CD14 ELISA, 65 CD14 Gene, 7 CD14 Lysate, 7 CD14 Protein, 3 CD14 qPCR. All CD14 reagents are ready to use.

CD14 Protein (7)

CD14 Antibody (39)

CD14 ELISA Kit & Match Antibody ELISA Pair Set (1)

CD14 cDNA Clone (65)

NM_000591.2
NM_009841.3
NM_021744.1
NM_001130433.1
XM_004802907.1

CD14 Lysate (7)

More Product Popular With Customers

CD14 Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 32 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.

CD14 References

  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • SD Wright, et al. (1990) CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science. 249 (4975): 1431-3.