>Rabbit PAb Antibody
>CSF2RB / CD131 Antibody (Antigen Affinity Purified)
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CSF2RB / CD131 Antibody ( Antigen Affinity Purified )
|Order or Inquire for CSF2RB Antibody product||Quality antibodies||Antibody production services|
|Detection limit is 0.5 ng/lane in WB|
|Detection limit is 0.00245 ng/well in ELISA|
CSF2RB / CD131 Antibody Product Information
Recombinant human CSF2RB protein ( Catalog#10516-H08H )
|Antibody Type :||Rabbit Polyclonal Antibody ( Antibody Purification Platform )|
|Ig Type :||
|Formulation :||0.2 μm filtered solution in PBS with 5% trehalose|
Produced in rabbits immunized with purified, human cell-derived, recombinant human CSF2RB ( rh CSF2RB ; Catalog#10516-H08H ; NP_000386.1 ; Met 1 - Trp 443 ). CSF2RB specific IgG was purified by human CSF2RB affinity chromatography
CSF2RB / CD131 Antibody Usage Guide
Human CSF2RB / CD131
|Western blot :||This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect CSF2Rb in WB. Using a DAB detection system, the detection limit for CSF2Rb is approximately 0.5 ng/lane under non-reducing conditions and reducing conditions.|
|Direct ELISA :||This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect human CSF2Rb. The detection limit for human CSF2Rb is approximately 0.00245 ng/well.|
|Storage :||This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
CSF2RB / CD131 Antibody Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|CD131/CSF2RB/IL3RB/IL5RB||Human||CD131/CSF2RB Protein, Recombinant||10516-H08H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|WB, ELISA||CD131/CSF2RB/IL3RB/IL5RB Antibody, Rabbit PAb||10516-RP01|
|WB, ELISA||CD131/CSF2RB/IL3RB/IL5RB Antibody, Rabbit PAb (Antigen Affinity Purified)||10516-RP02|
|WB, ELISA||CD131 / CSF2RB / IL3RB / IL5RB Antibody||10516-R001|
|WB, ELISA||CD131/CSF2RB/IL3RB/IL5RB Antibody, Mouse MAb||10516-MM11|
CSF2RB / CD131 Antibody Background
Colony stimulating factor 2 receptor, beta, low-affinity, also known as Cytokine receptor common subunit beta, CSF2RB, CDw131, and CD131, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 4 subfamily. It is a 897 amino acid protein which the sequence is further processed into a mature form. The cytokine receptor is a heterodimer of an alpha and a beta subunit, and this beta subunit (CD131) is also the common and high affinity receptor to the interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. It contains two fibronectin type-III domains. The WSXWS motif of CD131 appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif of CD131 is required for JAK interaction and/or activation.
- Mulhern, TD. et al., 2000, J. Mol. Biol. 297: 989-1001.
- Carr, PD. et al., 2001, Cell. 104: 291-300.
- Carr, PD. et al., 2006, Acta Crystallogr. F 62: 509-513
- Selleri, S. et al., 2008, J Transl Med. 6 : 17.