IL7R alpha (Protein|Antibody|cDNA Clone|ELISA Kit)

All IL7R alpha reagents are produced in house and quality controlled, including 19 IL7R alpha Antibody, 41 IL7R alpha Gene, 1 IL7R alpha IPKit, 6 IL7R alpha Lysate, 6 IL7R alpha Protein, 3 IL7R alpha qPCR. All IL7R alpha reagents are ready to use.

Recombinant IL7R alpha proteins are expressed by HEK293 Cells with fusion tags as C-His, C-mouse IgG1-Fc, C-human IgG1-Fc & His.

IL7R alphaantibodies are validated with different applications, which are ELISA, FCM, WB, IP.

IL7R alphacDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL7R alpha of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

IL7R alpha Protein (6)

Species

IL7R alpha Protein, Rat, Recombinant (Fc Tag)

80083-R05H

Expression host: HEK293 Cells

Rat IL7R/IL-7R/CD127 Protein 12375

IL7R alpha Protein, Cynomolgus, Recombinant (His Tag)

90332-C08H

Expression host: HEK293 Cells

Cynomolgus IL7R/IL-7R/CD127 Protein 12973

IL7R alpha Protein, Rat, Recombinant (His Tag)

80083-R08H

Expression host: HEK293 Cells

Rat IL7R/IL-7R/CD127 Protein 12376

IL7R alpha Protein, Mouse, Recombinant (His Tag)

50090-M08H

Expression host: HEK293 Cells

Mouse IL7R/IL-7R/CD127 Protein 11386

IL7R alpha Protein, Human, Recombinant (His & Fc Tag)

10975-H03H

Expression host: HEK293 Cells

Human IL7R/IL-7R/CD127 Protein 9264

IL7R alpha Protein, Human, Recombinant (His Tag)

10975-H08H

Expression host: HEK293 Cells

Human IL7R/IL-7R/CD127 Protein 9265
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IL7R alpha Antibody (19)

Application Clonality
Host

Anti-IL7R alpha Antibody (APC)

10975-R001-A

Application: FCM

Clonality: MAb

Human IL7R/IL-7R/CD127 Flow Cytometry (FC) 15078

Anti-IL7R alpha Antibody

50090-R201

Application: ELISA

Clonality: MAb

Anti-IL7R alpha Antibody

90332-RP01

Application: ELISA

Clonality: PAb

Anti-IL7R alpha Antibody

80083-RP01

Application: ELISA

Clonality: PAb

Anti-IL7R alpha Antibody

80083-T16

Application: ELISA

Clonality: PAb

Anti-IL7R alpha Antibody (PE)

10975-R001-P

Application: FCM

Clonality: MAb

Human IL7R/IL-7R/CD127 Flow Cytometry (FC) 5123

Anti-IL7R alpha Antibody

10975-R014

Application: FCM

Clonality: MAb

Human IL7R/IL-7R/CD127 Flow Cytometry (FC) 14056

Anti-IL7R alpha Antibody

10975-T48

Application: WB,ELISA

Clonality: PAb

Human IL7R/IL-7R/CD127 Western blot (WB) 13310

Anti-IL7R alpha Antibody

50090-RP01

Application: ELISA

Clonality: PAb

Anti-IL7R alpha Antibody

50090-RP02

Application: ELISA

Clonality: PAb

Anti-IL7R alpha Antibody

50090-T52

Application: WB,ELISA,IP

Clonality: PAb

Mouse IL7R/IL-7R/CD127 Western blot (WB) 14913

Anti-IL7R alpha Antibody (FITC)

10975-R001-F

Application: FCM

Clonality: MAb

Human IL7R/IL-7R/CD127 Flow Cytometry (FC) 5123

Anti-IL7R alpha Antibody

10975-MM12

Application: ELISA

Clonality: MAb

Anti-IL7R alpha Antibody (APC)

10975-R014-A

Application: FCM

Clonality: MAb

Human IL7R/IL-7R/CD127 Flow Cytometry (FC) 17157

Anti-IL7R alpha Antibody (PerCP)

10975-R001-C

Application: FCM

Clonality: MAb

Human IL7R/IL-7R/CD127 Flow Cytometry (FC) 15344

Anti-IL7R alpha Antibody

50090-R115

Application: ELISA

Clonality: MAb

Anti-IL7R alpha Antibody (FITC)

10975-R014-F

Application: FCM

Clonality: MAb

Human IL7R/IL-7R/CD127 Flow Cytometry (FC) 5124

Anti-IL7R alpha Antibody (PE)

10975-R014-P

Application: FCM

Clonality: MAb

Human IL7R/IL-7R/CD127 Flow Cytometry (FC) 5124

Anti-IL7R alpha Antibody

10975-R001

Application: ELISA,FCM

Clonality: MAb

Human IL7R/IL-7R/CD127 Flow Cytometry (FC) 5122
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IL7R alpha cDNA Clone (41)

Human
Mouse
Rat

IL7R alpha qPCR Primer (3)

IL7R alpha IP Kit (1)

IL7R alpha Lysate (6)

Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alpha (CD127) signaling is essential for T-cell development and regulation of naive and memory T-cell homeostasis. IL-7RA is critically required for the proper development and function of lymphoid cells. Therefore, the IL-7RA is critically required for the proper development and function of lymphoid cells. Studies from both pathogenic and controlled HIV infection indicate that the containment of immune activation and preservation of CD127 expression are critical to the stability of CD4(+) T cells in infection. A better understanding of the factors regulating CD127 expression in HIV disease, particularly on T(CM) cells, might unveil new approaches exploiting the IL-7/IL-7R receptor pathway to restore T cell homeostasis and promote immune reconstitution in HIV infection. Factors relevant to HIV infection that could potentially decrease CD127 expression on human CD8(+) T cells. CD127 down-regulation may be an important contributor to HIV-associated T-cell dysfunction. In addition to IL-7, IL-7RA also associates with TSLPR to form the functional receptor for thymic stromal lymphopoietin (TSLP) which indirectly regulates T cell development by modulating dendritic cell activation. Mutations in the human IL-7RA gene cause a type of severe combined immunodeficiency in which the major deficiencies are in T cell development, whereas B and NK cells are relatively normal in number. Variation in the IL7RA gene was recently found associated with multiple sclerosis (MS). The polymorphisms in the IL7RA gene is involved in MS pathogenesis and suggest that IL7RA variation may primarily affect chronic disease courses. Soluble CD127 (sCD127) appears to play an important role in the immunopathogenesis of several chronic infections, multiple sclerosis, and various cancers.

Protein
Antibody
Gene
qPCR
IPKit
Lysate
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