IL3RA (Protein|Antibody|cDNA Clone|ELISA Kit)

All IL3RA reagents are produced in house and quality controlled, including 6 IL3RA Antibody, 1 IL3RA ELISA, 39 IL3RA Gene, 1 IL3RA IPKit, 5 IL3RA Lysate, 5 IL3RA Protein, 2 IL3RA qPCR. All IL3RA reagents are ready to use.

Recombinant IL3RA proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc & His, C-His, C-human IgG1-Fc.

IL3RAantibodies are validated with different applications, which are WB, ELISA, IP, ELISA(Det), ELISA(Cap).

IL3RAcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL3RA of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

IL3RAELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.

IL3RA Protein (5)

Species

IL3RA Protein, Mouse, Recombinant (ECD, Fc Tag)

50810-M02H

Expression host: HEK293 Cells

Mouse IL3RA/CD123 Protein 11921

IL3RA Protein, Mouse, Recombinant (ECD, His Tag)

50810-M08H

Expression host: HEK293 Cells

Mouse IL3RA/CD123 Protein 11922

IL3RA Protein, Human, Recombinant (His Tag)

10518-H08H

Expression host: HEK293 Cells

Human IL3RA/CD123 Protein 8889

IL3RA Protein, Human, Recombinant (His & Fc Tag)

10518-H03H

Expression host: HEK293 Cells

Human IL3RA/CD123 Protein 8888

IL3RA Protein, Canine, Recombinant (His Tag)

70077-D08H

Expression host: HEK293 Cells

Canine IL3RA/CD123 Protein 12263
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IL3RA Antibody (6)

Application Clonality
Host

Anti-IL3RA Antibody

10518-MM07

Application: ELISA

Clonality: MAb

Anti-IL3RA Antibody

10518-RP01

Application: ELISA

Clonality: PAb

Anti-IL3RA Antibody

10518-R017

Application: WB,ELISA,IP

Clonality: MAb

Rat UCHL1 Immunoprecipitation(IP) 8269

Anti-IL3RA Antibody

10518-MM01

Application: ELISA(Cap)

Clonality: MAb

Anti-IL3RA Antibody

10518-R012

Application: ELISA,ELISA(Det)

Clonality: MAb

Anti-IL3RA Antibody

10518-RP02

Application: ELISA

Clonality: PAb

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IL3RA ELISA KIT & match antibody elias pair set ( 1 )

IL3RA Matched ELISA Antibody Pair Set,Human

SEK10518

Assay Range: 31.25 pg/ml

Human IL3RA/CD123 ELISA Pair Set Standard Curve 13851

IL3RA cDNA Clone (39)

Human
Canine
Mouse

IL3RA qPCR Primer (2)

IL3RA IP Kit (1)

IL3RA Lysate (5)

Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily. The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. The WSXWS motif of IL3RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box one motif of IL3RA is required for JAK interaction and / or activation. IL3RA represents a unique marker for primitive leukemic stem cells. Targeting of IL3RA may be a promising strategy for the preferential ablation of AML cells. Aberrant IL3RA expression is a good marker for monitoring of minimal residual disease. IL3RA is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. Recent studies have shown that interleukin-3 receptor alpha (CD123) is highly expressed on leukemia stem cells of patients with acute myeloid leukemia, and is correlated with tumor load and poor prognosis. CD123 was highly expressed in the bone marrow of the patients with myelodysplastic syndrome (MDS), significantly correlated with the proportion of bone marrow blasts, and thus might be the marker of MDS malignant clone. IL3RA is also a useful new marker for distinguishing B-cell disorders with circulating villous lymphocytes as its expression is characteristic of typical hairy cell leukemia (HCL) with high sensitivity and specificity.

Protein
Antibody
ELISA
Gene
qPCR
IPKit
Lysate
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