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> CD112 Protein & Antibody (Nectin-2, PVRL2) CD112 Protein & Antibody (Nectin-2, PVRL2)
Cluster of Differentiation 112 (Poliovirus Receptor-Related Protein 2)
CD112 Alternative Names
CD112, nectin-2, PVRL2, HVEB, PRR2, PVRR2 [ Homo sapiens ]
CD112, nectin-2, Pvrl2 , mHVEB, PRR2, AI325026, AI987993, MPH, Pvr, Pvs [ Mus musculus ]
CD112 Protein & Antibody
Sino Biological offers a comprehensive set of research tools (proteins, antibodies) for Cluster of differentiation (CD) related research. We offer CD proteins from human and mouse. Our antibody products include mouse monoclonal and rabbit polyclonal antibodies for application such as ELISA, Western Blotting, IHC, etc. All of our antibodies were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.
CD112 Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CD112/Nectin-2 | Human | CD112/Nectin-2 Protein, Recombinant |
10005-H08H |
| CD112/Nectin-2 | Human | CD112/Nectin-2/Fc Protein, Recombinant |
10005-H02H |
| CD112/Nectin-2 | Human | CD112/Nectin-2 Protein, Recombinant | 10005-HCCH |
| CD112/Nectin-2 | Mouse | CD112/Nectin-2 Protein, Recombinant | 50318-M08H |
| Nectin-2 | Rat | Nectin-2 / PVRL2 Protein, Recombinant | 80327-R08H |
CD112 Antibody
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human CD112/Nectin-2 |
ELISA | Mouse Monoclonal Antibody | 10005-MM01 |
| Human CD112/Nectin-2 |
WB FCM | CD112 / Nectin-2 / PVRL2 Antibody | 10005-MM11 |
| Human CD112/Nectin-2 |
WB FCM | CD112 / Nectin-2 / PVRL2 Antibody ( FITC ) | 10005-MM11-F |
| Human CD112/Nectin-2 |
WB, ELISA | CD112/Nectin-2 Antibody, Rabbit Mab | 10005-R107 |
| Human CD112/Nectin-2 |
IHC | CD112/Nectin-2 Antibody, Rabbit Mab | 10005-R005 |
| Human CD112/Nectin-2 |
ELISA | Rabbit Polyclonal Antibody | 10005-RP03 |
| Human CD112/Nectin-2 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 10005-RP04 |
| Mouse CD112/Nectin-2 |
WB, ELISA | CD112/Nectin-2 Antibody, Rabbit MAb | 50318-R110 |
| Mouse CD112/Nectin-2 |
WB, ELISA | Rabbit Polyclonal Antibody | 50318-RP01 |
| Mouse CD112/Nectin-2 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 50318-RP02 |
CD112 Related Areas
Cardiovascular>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>CD112/Nectin-2
Neuroscience>>Synaptic Protein>>CD112/Nectin-2
Stem Cell>>Neural Stem Cell (NSC)>>Neuronal Cell Markers>>CD112/Nectin-2
Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hemangioblast>>Endothelial Cell Marker>>CD112/Nectin-2
Cancer>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>CD112/Nectin-2
Immunology>>Adhesion Molecule>>Cell Adhesion Molecule (IgSF CAM)>>CD112/Nectin-2
Immunology>>Innate Immunity>>Natural Killer Cell (NK Cell)>>CD112/Nectin-2
Immunology>>Cluster of Differentiation>>Granulocyte CD Antigen>>Granulocyte Markers>>CD112/Nectin-2
Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Monocyte Markers>>CD112/Nectin-2
Immunology>>Cluster of Differentiation>>Natural Killer (NK) Cell CD Antigen>>CD112/Nectin-2
CD112 Related Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| CD155/PVR | Human | CD155/PVR Protein, Recombinant |
| CD155/PVR | Human | CD155/PVR/Fc Protein, Recombinant |
| CD155/PVR | Human | CD155/PVR Protein, Recombinant |
| CD155/PVR | Mouse | CD155/PVR Protein, Recombinant |
| CD155/PVR | Mouse | CD155/PVR/Fc Protein, Recombinant |
| CD155/PVR | Rat | CD155 Protein, Recombinant |
| CD155/PVR | Cynomolgus | CD155 Protein, Recombinant |
| CD226/DNAM-1 | Human | CD226/DNAM-1 Protein, Recombinant |
| CD226/DNAM-1 | Human | CD226/DNAM-1/Fc Protein, Recombinant |
| CD226/DNAM-1 | Mouse | CD226/DNAM-1 Protein, Recombinant |
| CD226/DNAM-1 | Mouse | CD226/DNAM-1/Fc Protein, Recombinant |
| TIGIT/VSTM3 | Human | TIGIT/VSTM3 Protein, Recombinant |
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| CD112/Nectin-2 | Human | Homo sapiens CD112/Nectin2 transcript variant alpha cDNA Clone(NM_002856.2) |
| CD155/PVR | Human | Homo sapiens CD155/PVR transcript variant 1 cDNA Clone(NM_006505.2) |
| CD155b | Human | Homo sapiens CD155b transcript variant 2 cDNA Clone(NM_001135768.1) |
| CD155 | Mouse | Mus musculus CD155/PVR cDNA Clone |
| CD155 | Rat | Rattus norvegicus CD155/PVR cDNA Clone |
| CD226/DNAM-1 | Human | Homo sapiens CD226/DNAM-1 cDNA Clone(NM_006566.2) |
| CD226/DNAM-1 | Mouse | Mus musculus CD226/DNAM-1 cDNA Clone |
| TIGIT/VSTM3 | Human | Homo sapiens TIGIT/VSTM3 cDNA Clone(NM_173799.2) |
CD112 Background
Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+ T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy.
CD112 Related Studies
- Bachelet I, et al. (2006) Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic process. J Biol Chem. 281(37): 27190-6.
- Wang L, et al. (2009) Molecular cloning, characterization and three-dimensional modeling of porcine nectin-2/CD112. Vet Immunol Immunopathol. 132(2-4): 257-63.
Nectin-2/CD112/PVRL2 related areas, pathways, and other information
