All CD10 reagents are produced in house and quality controlled, including 9 CD10 Antibody, 52 CD10 Gene, 1 CD10 IPKit, 6 CD10 Lysate, 6 CD10 Protein, 3 CD10 qPCR. All CD10 reagents are ready to use.
Recombinant CD10 proteins are expressed by HEK293 Cells with fusion tags as N-His, N-human IgG1-Fc, N-cleavage.
CD10antibodies are validated with different applications, which are ELISA, IHC-P, WB, IP, FCM, ICC/IF, IF.
CD10cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD10 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 10 (CD10), also known as Neprilysin and neutral endopeptidase, is a member of the CD system. CD10 is a zinc-dependent metalloprotease enzyme that had function to degrade a number of small secreted peptides such as the amyloid beta peptide. It exist as a membrane-bound protein and have high concentration in kidney and lung tissues. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process. CD10 is also associated with other biochemical processes.