All CCL27 reagents are produced in house and quality controlled, including 26 CCL27 Gene, 1 CCL27 Protein, 3 CCL27 qPCR. All CCL27 reagents are ready to use.
Recombinant CCL27 proteins are expressed by E. coli with fusion tags as N-His.
CCL27cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CCL27 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CCL27, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27 is chemotactic for skin-associated memory T lymphocytes. CCL27 may also play a role in mediating homing of lymphocytes to cutaneous sites. CCL27 plays a pivotal role in establishing the inflammatory infiltrate characteristic for common inflammatory skin diseases. Through binding to the chemokine receptor 10 (CCR10), CCL27 mediates inflammation by promoting lymphocyte migration into the skin.