All Eotaxin-2 reagents are produced in house and quality controlled, including 2 Eotaxin-2 Antibody, 36 Eotaxin-2 Gene, 1 Eotaxin-2 Lysate, 1 Eotaxin-2 Protein, 2 Eotaxin-2 qPCR. All Eotaxin-2 reagents are ready to use.
Recombinant Eotaxin-2 proteins are expressed by Baculovirus-Insect Cells with fusion tags as C-His.
Eotaxin-2antibodies are validated with different applications, which are ELISA.
Eotaxin-2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Eotaxin-2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Expression host: Baculovirus-Insect Cells
CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with aspirin-exacerbated respiratory disease.