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> CCL21 / 6Ckine Protein CCL21 / 6Ckine Protein
Chemokine (C-C motif) Ligand 21
CCL21 / 6Ckine Products
CCL21 / 6Ckine Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CCL21/6Ckine | Human | CCL21/6Ckine Protein, Recombinant, with Native |
10477-HNAB |
| CCL21/6Ckine | Cynomolgus | CCL21 / SCYA21 Protein, Recombinant, with Native | 90138-CNAB |
CCL21 / 6Ckine cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CCL21/6Ckine | Human | Human CCL21/6Ckine cDNA Clone / ORF Clone | HG10477-M |
| CCL21/6Ckine | Mouse | Mouse CCL21/6Ckine cDNA Clone / ORF Clone | MG50341-M |
| CCL21/6Ckine | Cynomolgus | Cynomolgus monkey CCL21 cDNA Clone / ORF Clone | CG90138-G |
CCL21 / 6Ckine Related Areas
Immunology>>Cytokine & Receptor>>Chemokine & Receptor>>CCL21/6Ckine
Immunology>>Adaptive Immunity>>T Cell>>T Cell Migration/Adhesion>>CCL21/6Ckine
CCL21 / 6Ckine Alternative Names
CCL21, 6Ckine, RP11-195F19.22-001, CKb9, ECL, MGC34555, SCYA21, SLC, TCA4 [Homo sapiens]
Ccl21a, 6Ckine, RP23-411B7.4, 6CKBAC2, ALP, AW987545, CKb9, MGC107632, SCYA21a, SLC, Scya21, Scya21b [Mus musculus]
CCL21 / 6Ckine Background
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 21(CCL21), also known as 6Ckine, exodus-2, and secondary lymphoid-tissue chemokine(SLC), is a small cytokine belonging to the C-C chemokine family. CCL21 takes its name 6Ckine for its consititutively six conserved cysteine residues but not four cysteines typical to chemokines. CCL21 has function in ininducing vigorous calcium migrations and chemotactic responses.
CCL21 / 6CkineRelated Studies
- Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
- Cocchi F, et al. (1995) Identification of RANTES, MIP-1a, and MIP-1b as the major HIV-suppressive factor produced by CD8+ T cells. Science. 270 (5243): 1811–5.
- Yoshida R, et al. (1998) Secondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7. The journal of biological chemistry. 273: 7118-22.
