MCP-1 / CCL2 cDNA ORF Clone in Cloning Vector, Human General Information
Same as Gene Bank Ref. ID sequence with the nucleotide 10T deletion mutation.
ORF Clone of Human chemokine (C-C motif) ligand 2 DNA.
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
MCP-1 / CCL2 cDNA ORF Clone in Cloning Vector, Human Alternative Names
GDCF-2 cDNA ORF Clone, Human;HC11 cDNA ORF Clone, Human;HSMCR30 cDNA ORF Clone, Human;MCAF cDNA ORF Clone, Human;MCP-1 cDNA ORF Clone, Human;MCP1 cDNA ORF Clone, Human;SCYA2 cDNA ORF Clone, Human;SMC-CF cDNA ORF Clone, Human
MCP-1 / CCL2 Background Information
Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection [7–9]. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
chemokine (C-C motif) ligand 2
Vásquez-Loarte T, Trubnykova M, Guio H. Genetic association meta-analysis: a new classification to assess ethnicity using the association of MCP-1 -2518 polymorphism and tuberculosis susceptibility as a model. BMC Genetics. 2015;16:128.