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Cynomolgus CCL17 / TARC Protein (His Tag)
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Cynomolgus CCL17 / TARC Protein (His Tag) (Cytokine) PDF Download

Catalog   Size (Price) Quantity In Stock Operation
90077-C08B  
YES   
 

Protein Production & Purification Service | Recombinant Cytokines & Growth Factors

Chemokine (C-C motif) ligand 17 Protein Datasheet

 

CCL17 / TARC Protein Price Inquiry ( Available Sizes )

CCL17 / TARC Protein Product Information

Synonym : CCL17, TARC
Protein Construction:

A DNA sequence encoding the cynomolgus CCL17 (Q8HYP9) (Met1-Ser94) was expressed with a polyhistidine tag at the C-terminus.

Source: Cynomolgus
Expression Host: Baculovirus-Insect cells

CCL17 / TARC Protein QC Testing

Purity: > 95 % as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

CCL17 / TARC protein

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Ala 24
Molecular Mass:

The recombinant heterodimer of cynomolgus CCL17 comprises 81 amino acids and has a calculated molecular mass of 9.5 KDa. The apparent molecular mass of the protein is approximately 10 KDa respectively in SDS-PAGE.

Formulation: Lyophilized from sterile 20mM Tris, 500mM NaCl,  pH 7.4, 10% gly.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.

CCL17 / TARC Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CCL17 / TARC Protein Related Products & Topics

Related Areas:

Immunology>>Cytokine & Receptor>>Chemokine & Receptor>>CCL17/TARC

Immunology>>Innate Immunity>>Monocyte/Macrophage>>Macrophage Marker>>CCL17/TARC

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CCL17/TARC Human CCL17/TARC Protein, Recombinant 10233-H08B
CCL17/TARC Human CCL17/TARC Protein, Recombinant, Native 10233-HNAB
CCL17/TARC Mouse CCL17 / TARC Protein, Recombinant 50046-MNAB
CCL17/TARC Cynomolgus CCL17 / TARC Protein, Recombinant 90077-C08B

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human CCL17/TARC WB, ELISA

CCL17 / TARC Antibody (Antigen Affinity Purified)

10233-RP02
Human CCL17/TARC WB, ELISA

CCL17 / TARC Antibody

10233-MM03

CCL17 / TARC Protein Description

C-C motif chemokine 17, also known as CC chemokine TARC, Small-inducible cytokine A17, Thymus and activation-regulated chemokine, CCL17 and SCYA17, is a secreted protein which belongs to the intercrine beta (chemokine CC) family. Chemokines are known to regulate the steady-state and inflammatory migration of cutaneous dendritic cells (DCs). The beta-chemokine CCL17, a ligand of CCR4, is inducibly expressed in a subset of DCs and is strongly up-regulated in atopic diseases. CCL17 / SCYA17 is constitutively expressed in the thymus and is produced by dendritic cells (DC), endothelial cells, keratinocytes (KC) and fibroblasts. CCL17 / SCYA17 is expressed at high levels in thymus and at low levels in the lung, colon and small intestine. CCL17 / SCYA17 is a chemotactic factor for T-lymphocytes but not monocytes or granulocytes. It may play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. CCL17 / SCYA17 binds to CCR4.Chemokine receptor CCR4 and its ligands (CCL17 and CCL22) are important for the recruitment of memory T cells into the skin in various cutaneous immune disease.

References

  1. Belperio JA. et al., 2004, J Immunol. 173 (7): 4692-8.
  2. Carpenter KJ. et al., 2005, Infect Immun. 73 (11): 7198-207.
  3. Saeki H. et al., 2006, J Dermatol Sci. 43 (2): 75-84.
  4. Niens M. et al., 2008, Br J Haematol. 140 (5): 527-36.
  5. Stutte S. et al., 2010, Proc Natl Acad Sci. 107 (19): 8736-41.
 

All Chemokine Proteins

Product name Product name
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CXCL4 / PF4 Protein (Native)CCL22 / MDC Protein (His Tag)
IL-8 (aa 1-77) ProteinMouse MIP3A / CCL20 Protein (His Tag)
IL-8 (aa 1-77) ProteinCCL24 / Eotaxin-2 / MPIF-2 Protein (His Tag)
IL-8 (aa 6-77) ProteinCXCL12 / SDF-1 (isoform a) Protein
IL-8 (aa 6-77) ProteinCynomolgus CCL21 / SCYA21 Protein (Native)
CCL5 Protein (Mucin-stalk Tag)FAM19A2 Protein
Mouse CXCL16 / SRPSOX Protein (His Tag)CXCL10 / Crg-2 Protein (Native)
CCL7 / MCP3 Protein (His Tag)Canine IL-8 / CXCL8 Protein (Native)
CCL8 / MCP-2 Protein (SUMO Tag)Rat CXCL16 / SRPSOX Protein
CXCL1 / MGSA / NAP-3 Protein (SUMO Tag)Cynomolgus CXCL7 / NAP-2 / PPBP Protein
CCL17 / TARC / SCYA17 Protein (His Tag)CXCL5 Protein (Native)
Mouse CXCL2 / GRO2 / MIP-2 (SUMO Tag)CCL1 / I-309 / TCA3 Protein (Native)
CCL15 / MIP-5 / NCC3 (aa 22-113) Protein (His Tag)Mouse CCL3 / Mip1a Protein (Native)
CCL17 / TARC / SCYA17 Protein (Native)Cynomolgus CCL17 / TARC Protein (His Tag)
Mouse CCL8 / MCP-2 Protein (NusA Tag)I-TAC / CXCL11 Protein (Native)
Mouse CCL6 / C-C motif ligand 6 Protein (His Tag)Mouse CXCL12 / SDF-1 Protein (Native)
Cynomolgus CXCL13 / BCA-1 / BLC Protein (His Tag)Cynomolgus CXCL9 motif chemokine 9 Protein (Native)
CXCL1 / MGSA / NAP-3 Protein (NusA Tag)Cynomolgus Interleukin 8 / IL8 Protein (Native)
Cynomolgus CXCL12 / SDF-1 ProteinCanine CXCL12 / SDF-1 Protein (Native)
Mouse CXCL9 / C-X-C motif chemokine 9 Protein (Native)Canine CXCL13 / BCA-1 Protein (His Tag)
CXCL9 / C-X-C motif chemokine 9 Protein (Native)Canine CXCL16 / SRPSOX Protein (His Tag)
CCL21 / SCYA21 Protein (Native)CCL27 / CTACK Protein (His Tag)
CCL14 / NCC2 Protein (His Tag)CXCL14 / BRAK Protein (Native)
Mouse CCL17 / TARC ProteinCCL23 / MIP 3 Protein (His Tag)
NCC2 / CCL14 (aa 28-93) Protein (His Tag)CCL23 / MIP 3 Protein
CCL7 / MCP3 Protein (His Tag)Canine CXCL16 / SRPSOX Protein
Mouse CCL1 / I-309 / TCA3 ProteinCanine CX3CL1 / Fractalkine / NTN Protein
CCL11 Protein (His Tag)Canine CX3CL1 / Fractalkine / NTN Protein
CXCL12 / SDF-1 Protein NativeCanine XCL1 Protein (His Tag)
Mouse XCL1 Protein (His Tag)MIP3A / CCL20 Protein (His Tag)
Rat CXCL7 / NAP-2 / PPBP ProteinRat CCL3 / Mip1a Protein (Native)
XCL1 Protein (His Tag)FAM19A4 / TAFA4 Protein
CCL15 / MIP-5 / NCC3 (aa 46-113) Protein (His Tag)CXCL7 / NAP-2 / PPBP Protein (His Tag)
XCL2 Protein (His Tag) 
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"