CCL17 / TARC Protein & Antibody

Chemokine (C-C motif) ligand 17 / Thymus and activation-regulated chemokine

CCL17 / TARC Products

CCL17 / TARC Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CCL17/TARC	Human	CCL17/TARC Protein, Recombinant	10233-H08B
CCL17/TARC	Human	CCL17/TARC Protein, Recombinant, Native	10233-HNAB
CCL17/TARC	Mouse	CCL17 / TARC Protein, Recombinant	50046-MNAB

CCL17 / TARC Antiobody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CCL17/TARC	WB, ELISA	CCL17 / TARC Antibody	10233-MM03

CCL17 / TARC cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CCL17/TARC	Human	CCL17/TARC cDNA Clone / ORF Clone	HG10233-M
CCL17/TARC	Mouse	CCL17/TARC cDNA Clone / ORF Clone	MG50046-M
CCL17/TARC	Cynomolgus	CCL17 cDNA Clone / ORF Clone	KG90077-G

CCL17 / TARC Related Areas

Immunology>>Cytokine & Receptor>>Chemokine & Receptor>>CCL17/TARC

Immunology>>Innate Immunity>>Monocyte/Macrophage>>Macrophage Marker>>CCL17/TARC

CCL17 / TARC Alternative Names

CCL17, TARC, A-152E5.3, ABCD-2, MGC138271, MGC138273, SCYA17 [Homo sapiens]

Ccl17, Tarc, Abcd-2, Scya17, Scya17l [Mus musculus]

CCL17 / TARC Background

Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.

CCL17 / TARC Related Studies

1. Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
2. Cocchi F, et al. (1995) Identification of RANTES, MIP-1a, and MIP-1b as the major HIV-suppressive factor produced by CD8⁺ T cells. Science. 270 (5243): 1811–5.
3. Morita A, et al. (2002). Evaluation of human thymus and activation-regulated chemokine concentrations in blood using a new sandwich ELISA based on monoclonal antibodies. Clin Chim Acta. 322 (1–2): 67–75.