Anti-TARC Antibody (PE)

Cat: 10233-MM02-P
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Anti-TARC Antibody (PE) (Mouse Monoclonal antibody) General Information
Product name
Anti-TARC Antibody (PE)
Validated applications
FCM
Species reactivity
Reacts with: Human
Specificity
Human TARC
Immunogen
Recombinant Human CCL17 / TARC protein (Catalog#10233-HNAB)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CCL17 / TARC (rh CCL17 / TARC; Catalog#10233-HNAB; Q92583-1; Met1-Ser94) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Source
Monoclonal Mouse IgG2b Clone #02
Purification
Protein A
Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Conjugate
PE
Concentration
10 μl/Test, 0.1 mg/ml
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Anti-TARC Antibody (PE) (Mouse Monoclonal antibody) Validated Applications

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-TARC Antibody (PE) (Mouse Monoclonal antibody) Images
Human CCL17/TARC Flow Cytometry (FC) 2635
Profile of anti-CCL17 reactivity on A549 cells analyzed by flow cytometry.
Anti-TARC Antibody (PE) Alternative Names
Anti-A-152E5.3 Antibody;Anti-ABCD-2 Antibody;Anti-SCYA17 Antibody;Anti-TARC Antibody
TARC Background Information

Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.

Full Name
chemokine (C-C motif) ligand 17
References
  • Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
  • Cocchi F, et al. (1995) Identification of RANTES, MIP-1a, and MIP-1b as the major HIV-suppressive factor produced by CD8+ T cells. Science. 270 (5243): 1811-5.
  • Morita A, et al. (2002). Evaluation of human thymus and activation-regulated chemokine concentrations in blood using a new sandwich ELISA based on monoclonal antibodies. Clin Chim Acta. 322 (1-2): 67-75.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-TARC Antibody Rabbit Polyclonal ELISA 50046-RP01
    Anti-TARC Antibody Rabbit Polyclonal ELISA 10233-T16
    Anti-TARC Antibody Mouse Monoclonal ELISA,ELISA(Cap) 10233-MM03
    Anti-TARC Antibody Mouse Monoclonal ELISA(Det) 10233-MM08
    Anti-TARC Antibody Rabbit Polyclonal ELISA 10233-RP01
    Anti-TARC Antibody Rabbit Polyclonal ELISA 10233-RP02
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