All MIP-5 reagents are produced in house and quality controlled, including 4 MIP-5 Antibody, 1 MIP-5 ELISA, 13 MIP-5 Gene, 2 MIP-5 Protein, 1 MIP-5 qPCR. All MIP-5 reagents are ready to use.
Recombinant MIP-5 proteins are expressed by E. coli with fusion tags as C-His.
MIP-5antibodies are validated with different applications, which are ELISA(Cap), ELISA.
MIP-5cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each MIP-5 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
MIP-5ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3.