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Product Catalog
> CCL14 / HCC-1 / HCC-3 Protein CCL14 / HCC-1 / HCC-3 Protein
Chemokine (C-C motif) Ligand 14 (Chemokine CC-1/CC-3)
CCL14 / HCC-1 / HCC-3 Products
CCL14 / HCC-1 / HCC-3 Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CCL14/HCC-1/HCC-3 | Human | CCL14/HCC-1/HCC-3 Protein, Recombinant | 10476-H07E |
| CCL14/HCC-1/HCC-3 | Human | NCC2 / CCL14 (aa 28-93) Protein, Recombinant |
10476-H07E1 |
CCL14 / HCC-1 / HCC-3 cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CCL14/HCC-1/HCC-3 | Human | Human CCL14/HCC-1/HCC-3 cDNA Clone / ORF Clone | HG10476-M |
CCL14 / HCC-1 / HCC-3 Related Areas
Immunology>>Cytokine & Receptor>>Chemokine & Receptor>>CCL14/HCC-1/HCC-3
CCL14 / HCC-1 / HCC-3 Alternative Names
CCL14, HCC-1, HCC-3, CC-1, CC-3, CKB1, MCIF, NCC2, SY14, NCC-2, SCYL2, SCYA14, FLJ16015, HCC-1(1-74), HCC-1/HCC-3 [Homo sapiens]
CCL14 / HCC-1 / HCC-3 Background
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 14 (CCL14), also known as HCC1 or HCC3, is a small cytokine belonging to the C-C chemoking family. CCL14 can be found in various tissues including spleen, bone marrow, muscle, gut, and liver. CCL14 activates monocytes, but does not induce their chemotaxis.
CCL14 / HCC-1 / HCC-3 Related Studies
- Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
- Knappe S, et al. (1996) HCC-1, a novel chemokine from human plasma. J Exp Med. 183: 295-9.
- Naruse, et al. (1996) A YAC contig of the human CC chemokine genes clustered on chromosome 17q11.2. Genomics. 34: 236-40.
