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CCDC134 Antibody, Mouse MAb

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    Human CCDC134 Antibody Product Information
    Immunogen:Recombinant Human CCDC134 protein (Catalog#13168-H08H)
    Clone ID:04
    Ig Type:Mouse IgG1
    Concentration:
    Endotoxin:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CCDC134 (rh CCDC134; Catalog#13168-H08H; Q9H6E4; Met 1-Leu 229). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
    Other CCDC134 Antibody Products
    Reactivity: Human  
    Application: ELISA  WB  IP  
    • Slide 1
    • Slide 1
    13168-T52-50
    13168-T52-200
    13168-T52-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      13168-RP01-400
      13168-RP01-200
      13168-RP01-100
      400 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: WB  IP  
      • Slide 1
      • Slide 1
      13168-R026-50
      13168-R026-100
      50 µg 
      100 µg 
      Add to Cart

      Anti-Histone H3 rabbit monoclonal antibody at 1:200 dilution

      Lane A: NIH3T3 Whole Cell Lysate

      Lane B: Hela Whole Cell Lysate

      Lysates/proteins at 30 μg per lane.

      Secondary

      Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size:15 kDa

      Observed band size:17 kDa

      CCDC134 Background

      Coiled-coil domain containing 134 (CCDC134) is a 229 amino acids secretory protein. Coiled-coil domain is a motif in which alpha-helix are coiled together. It has been found in many types of proteins, including transcription factors, intermediate filaments and certain tRNA synthetases. Many proteins containing such motif CCDC134 are involved in important biological functions. CCDC134 is also considered as a novel human MAPK-regulating protein that can inhibit the MAPK pathway. This protein significantly inhibite Elk1 transcriptional activity. The coiled-coil domain is a ubiquitous protein motif that is often involved in oligomerization.

      Human CCDC134 References
    • Huang J, et al. (2007) CCDC134, a novel secretory protein, inhibits activation of ERK and JNK, but not p38 MAPK. Cellular and Molecular Life Sciences. 65(2): 338-49.
    • Kim S, et al. (2011) Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort. Neurology. 76(1): 69-79.
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      All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"