Calsequestrin 1 cDNA ORF Clone in Cloning Vector, Human

Cat: HG13805-G
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All Calsequestrin 1 Reagents
CRO Services
Product recommended

All Calsequestrin 1 Reagents
Calsequestrin 1 cDNA ORF Clone in Cloning Vector, Human General Information
Gene
Species
Human
NCBI Ref Seq
RefSeq ORF Size
1173 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Human calsequestrin 1 (fast-twitch, skeletal muscle).
Plasmid
Vector
Sequencing Primers
SP6 and T7 or M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
Calsequestrin 1 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

Calsequestrin 1 cDNA ORF Clone in Cloning Vector, Human Alternative Names
CASQ cDNA ORF Clone, Human;PDIB1 cDNA ORF Clone, Human;VMCQA cDNA ORF Clone, Human
Calsequestrin 1 Background Information

Calsequestrin-1 is an isoform of calsequestrin. Calsequestrin is a calcium-binding protein of the sarcoplasmic reticulum. It helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction, even though the concentration of calcium in the sarcoplasmic reticulum is much higher than in the cytosol. Two forms of calsequestrin have been identified: Calsequestrin-2 and Calsequestrin-1. Calsequestrin-1 is found in fast skeletal muscle. The release of calsequestrin-bound calcium (through a calcium release channel) triggers muscle contraction. The active protein is not highly structured, more than 50% of it adopting a random coil conformation. When calcium binds there is a structural change whereby the alpha-helical content of the protein increases from 3 to 11%. Both forms of calsequestrin are phosphorylated by casein kinase 2, but the cardiac form is phosphorylated more rapidly and to a higher degree. Calsequestrin-1 is also secreted in the gut where it deprives bacteria of calcium ions.

Full Name
calsequestrin 1 (fast-twitch, skeletal muscle)
References
  • Slupsky JR, et al. (1987) Characterization of cardiac calsequestrin. Biochemistry. 26(20): 6539-44.
  • Cala SE, et al. (1991) Phosphorylation of cardiac and skeletal muscle calsequestrin isoforms by casein kinase II. Demonstration of a cluster of unique rapidly phosphorylated sites in cardiac calsequestrin. J Biol Chem. 266(1):391-8.
  • Wang S, et al. (1998) Crystal structure of calsequestrin from rabbit skeletal muscle sarcoplasmic reticulum. Nat Struct Biol. 5(6):476-83.
  • Calsequestrin 1 cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    Calsequestrin 1 cDNA ORF Clone in Cloning Vector, Mouse MG53155-G
    Calsequestrin 1 cDNA ORF Clone, Mouse, untagged MG53155-UT
    Calsequestrin 1 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG53155-ACG
    Calsequestrin 1 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG53155-ACGLN
    Calsequestrin 1 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG53155-ACR
    Calsequestrin 1 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG53155-CF
    Calsequestrin 1 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG53155-NF
    Calsequestrin 1 cDNA ORF Clone, Mouse, C-His tag MG53155-CH
    Calsequestrin 1 cDNA ORF Clone, Mouse, N-His tag MG53155-NH
    Calsequestrin 1 cDNA ORF Clone, Mouse, C-HA tag MG53155-CY
    Calsequestrin 1 cDNA ORF Clone, Mouse, N-HA tag MG53155-NY
    Calsequestrin 1 cDNA ORF Clone, Mouse, C-Myc tag MG53155-CM
    Calsequestrin 1 cDNA ORF Clone, Mouse, N-Myc tag MG53155-NM

    Calsequestrin 1 cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    Calsequestrin 1 cDNA ORF Clone, Human, untagged HG13805-UT
    Calsequestrin 1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG13805-ACGLN
    Calsequestrin 1 cDNA ORF Clone, Human, C-GFPSpark® tag HG13805-ACG
    Calsequestrin 1 cDNA ORF Clone, Human, C-OFPSpark® tag HG13805-ACR
    Calsequestrin 1 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG13805-CF
    Calsequestrin 1 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG13805-NF
    Calsequestrin 1 cDNA ORF Clone, Human, C-His tag HG13805-CH
    Calsequestrin 1 cDNA ORF Clone, Human, N-His tag HG13805-NH
    Calsequestrin 1 cDNA ORF Clone, Human, C-HA tag HG13805-CY
    Calsequestrin 1 cDNA ORF Clone, Human, N-HA tag HG13805-NY
    Calsequestrin 1 cDNA ORF Clone, Human, C-Myc tag HG13805-CM
    Calsequestrin 1 cDNA ORF Clone, Human, N-Myc tag HG13805-NM
    Calsequestrin 1 qPCR Primer Pairs, Human HP102478
    info info
    添加购物车成功! 添加购物车失败!