All CANT1 reagents are produced in house and quality controlled, including 30 CANT1 Gene, 2 CANT1 Lysate, 2 CANT1 Protein, 1 CANT1 qPCR. All CANT1 reagents are ready to use.
Recombinant CANT1 proteins are expressed by HEK293 Cells with fusion tags as N-human IgG1-Fc, N-His.
CANT1cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CANT1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CANT1(calcium activated nucleotidase 1) belongs to the apyrase family. Apyrase is a calcium-activated plasma membrane-bound enzyme (magnesium can also activate it) (EC 22.214.171.124) that catalyses the hydrolysis of ATP to yield AMP and inorganic phosphate. Two isoenzymes are found in commercial preparations from S. tuberosum. One with a higher ratio of substrate selectivity for ATP: ADP and another with no selectivity. It can also act on ADP and other nucleoside triphosphates and diphosphates with the general reaction being NTP -> NDP + Pi -> NMP + 2Pi. The salivary apyrases of blood-feeding arthropods are nucleotide hydrolysing enzymes are implicated in the inhibition of host platelet aggregation through the hydrolysis of extracellular adenosine diphosphate. CANT1 functions as a calcium-dependent nucleotidase with a preference for UDP. Defects in CANT1 are the cause of desbuquois dysplasia.