0 products, total $0.+86-400-890-9989      Login |  Register 中文한국어

Browse By Molecule:

Your Position: Home > CANT1 Protein

CANT1 Protein

calcium activated nucleotidase 1

CANT1 Products

CANT1 Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CANT1 Human CANT1 Protein, Recombinant 13124-H01H
CANT1 Human CANT1 Protein, Recombinant 13124-H07H

CANT1 cDNA Clone

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CANT1 Human CANT1 cDNA Clone / ORF Clone HG13124-G

CANT1 Related Areas

Enzyme>>Other>> CANT1

CANT1Alternative Names

DBQD, SCAN-1, SCAN1, SHAPY, Ca2+-dependent endoplasmic reticulum nucleoside diphosphatase, apyrase homolog, micromelic dwarfism with vertebral and metaphyseal abnormalities and advanced carpotarsal ossification, putative MAPK-activating protein PM09, putative NF-kappa-B-activating protein 107, soluble Ca-activated nucleotidase, isozyme 1, soluble calcium-activated nucleotidase 1, soluble calcium-activated nucleotidase SCAN-1 [Homo sapiens]

RP23-394O9.5, 5830420C20Rik, Apy1h, D11Bwg0554e, Entpd8, SCAN-1, Shapy, Ca2+-dependent endoplasmic reticulum nucleoside diphosphatase, apyrase 1, homolog (C. lectularius), apyrase homolog, soluble calcium-activated nucleotidase 1 [Mus musculus]

CANT1 Background

CANT1(calcium activated nucleotidase 1) belongs to the apyrase family. Apyrase is a calcium-activated plasma membrane-bound enzyme (magnesium can also activate it) (EC 3.6.1.5) that catalyses the hydrolysis of ATP to yield AMP and inorganic phosphate. Two isoenzymes are found in commercial preparations from S. tuberosum. One with a higher ratio of substrate selectivity for ATP: ADP and another with no selectivity. It can also act on ADP and other nucleoside triphosphates and diphosphates with the general reaction being NTP -> NDP + Pi -> NMP + 2Pi. The salivary apyrases of blood-feeding arthropods are nucleotide hydrolysing enzymes are implicated in the inhibition of host platelet aggregation through the hydrolysis of extracellular adenosine diphosphate. CANT1 functions as a calcium-dependent nucleotidase with a preference for UDP. Defects in CANT1 are the cause of desbuquois dysplasia.

CANT1 Related Studies

  1. Failer BU, et al. (2002) Cloning, expression, and functional characterization of a Ca(2+)-dependent endoplasmic reticulum nucleoside diphosphatase. J Biol Chem. 277(40):36978-86.
  2. Smith TM, et al. (2002) Cloning, expression, and characterization of a soluble calcium-activated nucleotidase, a human enzyme belonging to a new family of extracellular nucleotidases. Arch Biochem Biophys. 406(1):105-15.
  3. Strausberg RL, et al. (2003) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903.

 

 

CANT1 related areas, pathways, and other information

 

 

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
_×