Anti-CAMKIV Antibody

Cat: 50838-RP01
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Anti-CAMKIV Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CAMKIV Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Mouse
Specificity
Mouse CAMKIV
Immunogen
Recombinant Mouse CAMK4 / CaMKIV protein (Catalog#50838-M20B)
Preparation
Produced in rabbits immunized with purified, recombinant Mouse CAMK4 / CaMKIV (rM CAMK4 / CaMKIV; Catalog#50838-M20B; P08414; Met1-Tyr469). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CAMKIV Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CAMKIV Antibody Alternative Names
Anti-A430110E23Rik Antibody;Anti-AI666733 Antibody;Anti-CaMKIV Antibody;Anti-CaMKIV/Gr Antibody;Anti-D18Bwg0362e Antibody
CAMKIV Background Information

Ca2+/ calmodulin-dependent protein kinase 4 (CAMKⅣ) belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme implicated in the phophoinositide amplification cascade. Ca2+/calmodulin dependent protein kinase (CAMK) can be activated by the introcellular increased Ca2+ and then apt to combine with the target protein. Ca2+/ calmodulin-dependent protein kinase 4 (CAMKⅣ) is a multifunctional CaM-dependent kinase protein with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. All of the isforms of this family, including myosin light chain kinase, phosphorylase kinase, CaMK1, CaMKⅢ and CaMKⅣ have EF-hand structure.

Full Name
calcium/calmodulin-dependent protein kinase IV
References
  • Feliciano DM, et al. (2009) Repression of Ca2+/calmodulin-dependent protein kinase IV signaling accelerates retinoic acid-induced differentiation of human neuroblastoma cells. J Biol Chem. 284 (39): 26466-81.
  • Zhao X, et al. (2001). The modular nature of histone deacetylase HDAC4 confers phosphorylation-dependent intracellular trafficking. J Biol Chem. 276 (37): 35042-8.
  • Racioppi L, et al. (2008) Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CAMKIV Antibody Rabbit Polyclonal WB,ELISA,IHC-P,IP 50838-RP02
    Anti-CAMKIV Antibody Rabbit Monoclonal ELISA 50838-R162
    Anti-CAMKIV Antibody Rabbit Monoclonal IHC-P 50838-R001
    Anti-CAMKIV Antibody Rabbit Polyclonal WB,ICC/IF,IF 100744-T34
    Anti-CAMKIV Antibody Rabbit Polyclonal WB,IP 100744-T36
    Anti-CAMKIV Antibody Rabbit Polyclonal IHC-P,ICC/IF,IF 100746-T10
    Anti-CAMKIV Antibody Rabbit Polyclonal ICC/IF,IF 100868-T34
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