CAMK2A Protein

Calcium/calmodulin-dependent protein kinase II alpha

CAMK2A Products

CAMK2A Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
CAMK2A	Human	CAMK2A Protein, Recombinant, With GST Tag	10648-H09B

CAMK2A cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
CAMK2A	Human	Homo sapiens CAMK2A cDNA Clone	HG10648-M
CAMK2A	Mouse	Mouse CAMK2A cDNA gene Clone / ORF gene clone	MG50848-G

CAMK2A Related Areas

Stem Cell>>Wnt Signaling Pathway>>Non-Canonical Wnt Pathway>>CAMK2A

Neuroscience>>Axon Guidance>>Wnt Signaling Pathway>>CAMK2A

Neuroscience>>Synaptic Proteins>>CAMK2A

Enzyme>>Protein Kinase>>Intracellular Kinase>>CaM Kinase>>CAMK2A

Signal Transduction>>Calcium Signaling>>CaM Kinase>>CAMK2A

Signal Transduction>>Wnt Signaling Pathway>>Non-Canonical Wnt Pathway>>CAMK2A

Signal Transduction>>Protein Kinase>>Intracellular Kinase>>CAMK2A

CAMK2A Alternative Names

CAMK2A, CAMKA, KIAA0968 [Homo sapiens]

Camk2a, CaMKII, CaMK II, R74975, mKIAA0968 [Mus musculus]

CAMK2A Background

Ca²⁺/calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms, belongs to the Ca²⁺/ calmodulin-dependent protein kinase subfamily. CaM kinase Ⅱ is thought to be an important mediator of learning and memory and is also necessary for Ca²⁺ homeostasis and reuptake in cardiomyocytes chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CAMKIIA is one of the major forms of CAMKII. It has been found to play a critical role in sustaining activation of CAMKII at the postsynaptic density. Studies have found that knockout mice without CAMKIIA demonstrate a low frequency of LTP. Additionally, these mice do not form persistent, stable place cells in the hippocampus.

CAMK2A Related Studies

Lin CR, et al. (1987). Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase. Proc Natl Acad Sci U S A. 84 (16): 5962–6.
Walikonis RS, et al. (2001) Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin. J Neurosci. 21 (2): 423–33.
Gardoni F, et al. (2003) CaMKII-dependent phosphorylation regulates SAP97/NR2A interaction. J Biol Chem. 278 (45): 44745–52.