All CaMKII alpha reagents are produced in house and quality controlled, including 2 CaMKII alpha Antibody, 30 CaMKII alpha Gene, 1 CaMKII alpha Lysate, 1 CaMKII alpha Protein, 2 CaMKII alpha qPCR. All CaMKII alpha reagents are ready to use.
Recombinant CaMKII alpha proteins are expressed by Baculovirus-Insect Cells with fusion tags as N-GST.
CaMKII alphaantibodies are validated with different applications, which are IHC-P, ELISA.
CaMKII alphacDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CaMKII alpha of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Expression host: Baculovirus-Insect Cells
Ca2+/calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms, belongs to the Ca2+/ calmodulin-dependent protein kinase subfamily. CaM kinase Ⅱ is thought to be an important mediator of learning and memory and is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CAMKIIA is one of the major forms of CAMKII. It has been found to play a critical role in sustaining activation of CAMKII at the postsynaptic density. Studies have found that knockout mice without CAMKIIA demonstrate a low frequency of LTP. Additionally, these mice do not form persistent, stable place cells in the hippocampus.