All CALML5 reagents are produced in house and quality controlled, including 6 CALML5 Antibody, 2 CALML5 ELISA, 15 CALML5 Gene, 1 CALML5 Protein, 1 CALML5 qPCR. All CALML5 reagents are ready to use.
Recombinant CALML5 proteins are expressed by E. coli with fusion tags as N-GST & His.
CALML5antibodies are validated with different applications, which are ELISA, ICC/IF, IF, IHC-P, ELISA(Det), ELISA(Cap).
CALML5cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CALML5 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CALML5ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains four EF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5 / CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5 / CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5 / CLSP have been characterized by NMR spectroscopy. The mobility of CALML5 / CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain.