Anti-CALML5 Antibody

Cat: 11783-MM01
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All CALML5 Reagents
CRO Services
Product recommended

All CALML5 Reagents
Anti-CALML5 Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-CALML5 Antibody
Validated applications
ELISA,ELISA(Det)
Species reactivity
Reacts with: Human
Specificity
Human CALML5
No cross-reactivity in ELISA with E.coli cell lysate
Immunogen
Recombinant Human CALML5 protein (Catalog#11783-H20E)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CALML5 (rh CALML5; Catalog#11783-H20E; AAH39172.1; Met 1-Glu 146). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG1 Clone #2A3E2
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CALML5 Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  
ELISA(Det) 1:1000-1:10000 This antibody will detect Human CALML5 in ELISA pair set (Catalog: # SEK11783). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 11783-MM08).

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CALML5 Antibody Alternative Names
Anti-CLSP Antibody
CALML5 Background Information

Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains four EF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5 / CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5 / CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5 / CLSP have been characterized by NMR spectroscopy. The mobility of CALML5 / CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain.

Full Name
calmodulin like 5
References
  • Mehul B., et al., 2000, J. Biol. Chem. 275:12841-12847.
  • Babini E., et al., 2006, Structure 14:1029-1038.
  • Kawabata,K. et al., 2007, Gene Ther. 14 (16):1199-207.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CALML5 Antibody Rabbit Polyclonal ELISA 11783-RP01
    Anti-CALML5 Antibody Rabbit Monoclonal IHC-P 11783-R119
    Anti-CALML5 Antibody Mouse Monoclonal ELISA(Cap) 11783-MM08
    Anti-CALML5 Antibody Rabbit Monoclonal ELISA,ICC/IF,IF 11783-R158
    Anti-CALML5 Antibody Rabbit Polyclonal ELISA,IHC-P 11783-RP02
    info info
    添加购物车成功! 添加购物车失败!