CALML3 (Protein|Antibody|cDNA Clone|ELISA Kit)

All CALML3 reagents are produced in house and quality controlled, including 5 CALML3 Antibody, 2 CALML3 Gene, 1 CALML3 IPKit, 1 CALML3 Protein, 1 CALML3 qPCR. All CALML3 reagents are ready to use.

Recombinant CALML3 proteins are expressed by E. coli with fusion tags as N-His.

CALML3 antibodies are validated with different applications, which are ELISA, WB, IHC-P, IP, FCM, ICC/IF, IF.

CALML3 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CALML3 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

CALML3 Protein (1)

Species

CALML3 Protein, Human, Recombinant (His Tag)

12480-H07E

Expression host: E. coli

Human CALML3 Protein 10072
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CALML3 Antibody (5)

Application Clonality
Host

Anti-CALML3 Antibody

12480-RP02

Specificity: Human

Application: WB,ELISA,IHC-P,IP

Clonality: PAb

Human CALML3 Immunohistochemistry(IHC) 4611

Anti-CALML3 Antibody

12480-MM02

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-CALML3 Antibody

12480-MM03

Specificity: Human

Application: FCM,ICC/IF,IF

Clonality: MAb

Human CALML3 Immunofluorescence(IF) 2993

Anti-CALML3 Antibody

12480-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-CALML3 Antibody

12480-R004

Specificity: Human

Application: ELISA

Clonality: MAb

Go

CALML3 cDNA Clone (2)

Human
NM_005185.2

CALML3 qPCR Primer (1)

CALML3 IP Kit (1)

Calmodulin-like protein 3 (CALML3) is similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinity, to cellular substrates. Calmodulin-like protein 3 (CALML3) is a tumor-sensitive protein specifically expressed in normal epithelial cells but downregulated in tumorigenesis. Downregulation of the protein is an early event in breast cancer development. One of the most pressing questions raised by the discovery of CLP/CALML3 is that of its potential targets. Although it is 85% identical to human calmodulin, the distinct properties of CLP suggest that it has specific targets or targets that only partially overlap with those of calmodulin. Research has identified the unconventional myosin-1 (Myo1) as a specific target of CALML3. The discovery of Myo1 as a specific target of CALML3 is highly significant and suggests multiple lines of further research such as investigations of the Ca2+ regulation of Myo1 and the role of the loss of CLP in epithelial differentiation, adhesion, and cancer. Cells expressing CALML3 displayed a striking increase in the number and length of myosin-1-positive filopodia and showed increased mobility in a wound healing assay.
Protein
Antibody
Gene
qPCR
IPKit
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