CADM4 (Protein|Antibody|cDNA Clone|ELISA Kit)

All CADM4 reagents are produced in house and quality controlled, including 1 CADM4 Antibody, 26 CADM4 Gene, 3 CADM4 Lysate, 3 CADM4 Protein, 1 CADM4 qPCR. All CADM4 reagents are ready to use.

Recombinant CADM4 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His.

CADM4antibodies are validated with different applications, which are WB.

CADM4cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CADM4 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

CADM4 Protein (3)

Species

CADM4 Protein, Human, Recombinant (ECD, His Tag)

16033-H08H

Expression host: HEK293 Cells

Human CADM4/IGSF4C/NECL-4 Protein 10912

CADM4 Protein, Mouse, Recombinant (His Tag)

50501-M08H

Expression host: HEK293 Cells

Mouse CADM4/IGSF4C/NECL-4 Protein 11688

CADM4 Protein, Human, Recombinant (Fc Tag)

16033-H02H

Expression host: HEK293 Cells

Human CADM4/IGSF4C/NECL-4 Protein 10911
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CADM4 Antibody (1)

Application
Clonality
Host

Anti-CADM4 Antibody

100945-T32

Application: WB

Clonality: PAb

Human CADM4/IGSF4C/NECL-4 Western blot (WB) 6860
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CADM4 cDNA Clone (26)

Human
Mouse

CADM4 qPCR Primer (1)

CADM4 Lysate (3)

Immunoglobulin superfamily member 4C (IGSF4C), also known as CADM4 or NECL-4, is an immunoglobulin (Ig) superfamily molecule showing significant homology with a lung tumor suppressor, TSLC1. CADM4/IGSF4C/NECL-4 protein is mainly expressed in the kidney, bladder, and prostate in addition to the brain. Experiments have reported the biological significance of CADM4/IGSF4C/NECL-4 in the urinary tissues. An immunohistochemical study reveals that CADM4 is expressed at the cell-cell attachment sites in the renal tubules, the transitional epithelia of the bladder, and the glandular epithelia of the prostate. IGSF4-immunoreactivity (IR) was observed diffusely in the telencephalic wall, whereas it became rather confined to the subplate, the cortical plate and the subventricular zone as the development proceeded. IGSF4-IR gradually decreased after birth and disappeared in adulthood. IGSF4 remained at low levels throughout embryonic stage, whereas it increased after birth. These spatiotemporal patterns of the expression suggest that IGSF4 plays crucial roles in the development of both telencephalon and cerebellum. CADM4/IGSF4C/NECL-4 is ectopically expressed in adult T-cell leukemia (ATL) cells, providing not only a diagnostic marker for ATL, but also a possible therapeutic target against its invasion. The distinct roles of CADM4/IGSF4C/NECL-4 in the oncogenesis of carcinomas and ATL could be due to tissue-specific differences in the downstream cascades, and is a novel concept with respect to cell adhesion in human oncogenesis.

Protein
Antibody
Gene
qPCR
Lysate
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