Anti-CABP5 Antibody

Cat: 13896-RP01
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Anti-CABP5 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CABP5 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human CABP5
Immunogen
Recombinant Human CABP3 / CABP5 protein (Catalog#13896-H07E)
Preparation
Produced in rabbits immunized with purified, recombinant Human CABP3 / CABP5 (rh CABP3 / CABP5; Catalog#13896-H07E; Q9NP86; Met1-Arg173). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CABP5 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CABP5 Antibody Alternative Names
Anti-CABP3 Antibody
CABP5 Background Information

CABP3, also known as CABP5, belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Expression of CABP3 gene is retina-specific. The mouse homolog of CABP3 has been shown to express in the inner nuclear layer of the retina, suggested its role in neuronal functioning. The specific function of CABP3 gene is unknown. Study of the transcripts and genomic structure revealed that the 5 end of this gene is complementary and reverse to that of the CABP5 gene, and the sequence beyond the overlapping region is nearly identical to that of CABP5. Thus, these two genes encode the protein products with distinct N-terminal halves but identical C-terminal halves. CABP3 inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. It is also involved in the transmission of light signals.

Full Name
calcium binding protein 5
References
  • McCauliffe DP, et al. (1990) A human Ro/SS-A autoantigen is the homologue of calreticulin and is highly homologous with onchocercal RAL-1 antigen and an aplysia memory molecule. J Clin Invest. 86(1):332-5.
  • Beutler E, et al. (1997) HLA-H and associated proteins in patients with hemochromatosis. Mol Med. 3(6):397-402.
  • Michalak M, et al. (2002) Calreticulin in cardiac development and pathology. Biochim Biophys Acta. 1600(1-2):32-7.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CABP5 Antibody Rabbit Polyclonal ELISA 13896-T16
    Anti-CABP5 Antibody Mouse Monoclonal ELISA 13896-MM08
    Anti-CABP5 Antibody Rabbit Monoclonal ELISA 13896-R016
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